How to Take Lugol's Iodine Orally

Co-authored by Mohammad Dar, MD and Hannah Madden

Last Updated: January 11, 2023 References

Lugol’s iodine, sometimes called Lugol’s Solution or Lugol’s Strong Iodine Solution, is a combination of iodine and potassium iodide.^{[1]
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Research source} While it’s usually used as a topical treatment to prevent skin infections, your doctor may prescribe it orally to treat a variety of thyroid conditions. To use Lugol’s safely and effectively, make sure to follow your doctor’s instructions carefully. Additionally, be on the lookout for side effects or signs of an allergic reaction.

Question 1 of 9:

What is Lugol’s iodine used for?

It can improve or shrink nodules on your thyroid. Lugol’s iodine is a mixture of iodine and potassium iodide. Most often, a doctor will prescribe it to you for thyroid issues. It can also help improve thyroid storm, a severe condition where your thyroid produces too much of a hormone.^{[2]
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Question 2 of 9:

Do you need a prescription for Lugol’s iodine?

Yes, you’ll need a doctor’s prescription to get Lugol’s iodine. They’ll be able to tell you how much to take and how often to take it. If you have thyroid issues and you think Lugol’s iodine would be helpful, make an appointment with a healthcare provider.^{[4]
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Question 3 of 9:

How many drops should I take per day?

It depends on your age, weight, and medical condition. Lugol’s Solution is typically administered orally in very small doses—typically in drops rather than in milliliters. Make sure you thoroughly understand your doctor’s dosing instructions before taking the medication in order to avoid a dangerous overdose.^{[5]
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- If you’re not sure whether your dosing information is correct, double check with your doctor and your pharmacist.
- Pay attention to the frequency of the doses as well as the amount that you are supposed to take.
- For example, if you’re an adult taking Lugol’s in preparation for thyroid surgery, your doctor will likely instruct you to take 5 to 7 drops 3 times daily for 10 days before the operation.^{[6]
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Question 4 of 9:

What makes Lugol’s iodine taste better?

Juice, water, and broth can all help with the bitter taste. Lugol’s Solution by itself can be unpleasant-tasting and hard on your stomach. Ask your doctor if you can mix your dose in with another liquid to make it more palatable.^{[7]
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Research source} Make sure to drink the entire amount of liquid so that you get the full dosage of medicine.^{[8]
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- If the medicine upsets your stomach, try mixing it with milk or taking it with a meal.
- If you’re giving the medication to an infant or child, ask their doctor if you can mix it with juice, formula, or milk.

Question 5 of 9:

What do I do if I miss a dose of Lugol’s iodine?

Take your dose as soon as you remember. If it’s already time for your next dose, however, you should skip the dose you missed and take the next dose as you normally would. Don’t take 2 doses together if you miss a dose, as this could result in an overdose. ^{[9]
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Question 6 of 9:

What are the side effects of taking Lugol’s iodine?

Diarrhea, stomach pain, and nausea are common side effects. They may go away on their own as your body adjusts to the iodine. If you’re having stomach issues, try taking your dosage with a meal to help settle your stomach.^{[10]
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- Many people experience no side effects when taking Lugol’s iodine.

Question 7 of 9:

What are the signs of an overdose of Lugol’s iodine?

Pain, vomiting, confusion, and confusion are all signs of an overdose. You might also experience difficulty breathing, dizziness, loss of consciousness, or a metallic taste in the mouth. If this happens to you, call emergency services or head to the emergency room right away.^{[11]
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Question 8 of 9:

Will iodine make me gain weight?

If you take too much, it could make you gain weight over time. A side effect of too much iodine is a slow metabolism, which can lead to increased weight gain. Stick to the dose that your doctor recommends to avoid this side effect.^{[12]
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Question 9 of 9:

Can I take Lugol’s iodine while pregnant or breastfeeding?

Experts aren’t sure yet. There haven’t been any studies done on the health and safety of a baby ingesting Lugol’s iodine. If you are pregnant or breastfeeding, talk to your doctor and weigh the pros and cons carefully before taking any doses.^{[13]
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