Microbiology
Textbooks
Boundless Microbiology
Microbiology Textbooks Boundless Microbiology
Microbiology Textbooks
Microbiology

Chapter 5

Microbial Metabolism

Book Version 6
By Boundless
Boundless Microbiology
Microbiology
by Boundless
View the full table of contents
Section 1
Types of Metabolism
Thumbnail
Photoautotrophs and Photoheterotrophs

Photoautotrophs and photoheterotrophs are organisms that rely on light as their source of energy to carry out cellular processes.

Thumbnail
Chemoautotrophs and Chemoheterotrophs

Chemoautotrophs and chemoheterotrophs make their food using chemical energy rather than solar energy.

Section 2
Energy Production
Thumbnail
Control of Catabolic Pathways

Catabolic pathways are controlled by enzymes, proteins, electron carriers, and pumps that ensure that the remaining reactions can proceed.

Thumbnail
Transforming Chemical Energy

Cellular respiration is the process of transforming chemical energy into forms usable by the cell or organism.

Thumbnail
Connecting Other Sugars to Glucose Metabolism

Sugars, such as galactose, fructose, and glycogen, are catabolized into new products in order to enter the glycolytic pathway.

Section 3
Catabolism
Thumbnail
Types of Catabolism

Catabolism is the set of metabolic processes that break down large molecules.

Thumbnail
Pyruvic Acid and Metabolism

Pyruvic acid (CH3COCOOH) is an organic acid, a ketone, and the simplest of the alpha-keto acids.

Section 4
Glycolysis
Thumbnail
Importance of Glycolysis

Glycolysis is the first step in the breakdown of glucose to extract energy for cellular metabolism.

Thumbnail
Electron Donors and Acceptors

Electrons can enter the electron transport chain at three levels: dehydrogenase, the quinone pool, or a mobile cytochromeelectron carrier.

Thumbnail
ATP Yield

The amount of energy (as ATP) gained from glucose catabolism varies across species and depends on other related cellular processes.

Thumbnail
Respiration and Proton Motive Force

Respiration is one of the key ways a cell gains useful energy to fuel cellular activity.

Section 5
Respiratory ETS and ATP Synthase
Thumbnail
Cofactors and Energy Transitions

A cofactor is a non-protein chemical compound that is bound to a protein and is required for the protein's biological activity.

Thumbnail
Oxidoreductase Protein Complexes

In biochemistry, an oxidoreductase is an enzyme that catalyzes the transfer of electrons from one molecule to another.

Thumbnail
F10 ATP Synthase

ATP synthase is an important enzyme that provides energy for the cell to use through the synthesis of adenosine triphosphate.

Thumbnail
Sodium Pumps as an Alternative to Proton Pumps

Most bacteria rely on proton motive force as a source of energy for a variety of cellular processes.

Section 6
The Citric Acid (Krebs) Cycle
Thumbnail
Citric Acid Cycle

The citric acid cycle is a series of reactions that produces two carbon dioxide molecules, one GTP/ATP, and reduced forms of NADH and FADH2.

Thumbnail
Breakdown of Pyruvate

After glycolysis, pyruvate is converted into acetyl CoA in order to enter the citric acid cycle.

Thumbnail
Acetyl CoA and the Citric Acid Cycle

The citric acid cycle is a key component of the metabolic pathway by which all aerobic organisms generate energy.

Section 7
Alternatives to Glycolysis
Thumbnail
The Entner–Doudoroff Pathway

The Entner–Doudoroff pathway is an alternate series of reactions that catabolize glucose to pyruvate.

Thumbnail
Aerobic Hydrocarbon Oxidation

Microbes can utilize hydrocarbons via oxidation as an energy source.

Thumbnail
The Pentose Phosphate Shunt

The pentose phosphate pathway (PPP) converts glucose-6-phosphate into NADPH and pentoses (5-carbon sugars).

Thumbnail
Organic Acid Metabolism

Microbes can harness energy and carbon derived from organic acids by using a variety of dedicated metabolic enzymes.

Thumbnail
Lipid Metabolism

Biological lipids, which are broken down and utilized though β-oxidation, represent a potent energy source.

Thumbnail
Connecting Proteins to Glucose Metabolism

Excess amino acids are converted into molecules that can enter the pathways of glucose catabolism.

Thumbnail
Methylotrophy and Methanotrophy

Methylotrophs and methanotrophs are a diverse group of microorganisms that can derive energy from the metabolism of single-carbon compounds.

Section 8
Fermentation
Thumbnail
Anaerobic Cellular Respiration

Some prokaryotes and eukaryotes use anaerobic respiration in which they can create energy for use in the absence of oxygen.

Thumbnail
Clostridial and Propionic Acid Fermentation

Acetogenesis is a biological reaction wherein volatile fatty acids are converted into acetic acid, carbon dioxide, and hydrogen.

Thumbnail
Fermentation Without Substrate-Level Phosphorylation

Fermentation is the process of extracting energy from the oxidation of organic compounds such as carbohydrates.

Thumbnail
Syntrophy

Syntrophy is the phenomenon where one species lives off the products of another species.

Section 9
Anaerobic Respiration
Thumbnail
Electron Donors and Acceptors in Anaerobic Respiration

In anaerobic respiration, a molecule other than oxygen is used as the terminal electron acceptor in the electron transport chain.

Thumbnail
Nitrate Reduction and Denitrification

Denitrification is a type of anaerobic respiration that uses nitrate as an electron acceptor.

Thumbnail
Sulfate and Sulfur Reduction

Sulfate reduction is a type of anaerobic respiration that utilizes sulfate as a terminal electron acceptor in the electron transport chain.

Thumbnail
Methanogenesis

Methanogenesis is a form of anaerobic respiration that uses carbon as a electron acceptor and results in the production of methane.

Thumbnail
Proton Reduction

Anaerobic respiration utilizes highly reduced species - such as a proton gradient - to establish electrochemical membrane gradients.

Thumbnail
Anoxic Hydrocarbon Oxidation

Anoxic hydrocarbon oxidation can be used to degrade toxic hydrocarbons, such as crude oil, in anaerobic environments.

Section 10
Chemolithotrophy
Thumbnail
The Energetics of Chemolithotrophy

Chemolithotrophs use electron donors oxidized in the cell, and channel electrons into respiratory chains, producing ATP.

Thumbnail
Hydrogen Oxidation

While there are several mechanisms of anaerobic hydrogen oxidation, organisms can also use hydrogen as an energy source aerobically.

Thumbnail
Oxidation of Reduced Sulfur Compounds

Sulfur oxidation involves the oxidation of reduced sulfur compounds, inorganic sulfur, and thiosulfate to form sulfuric acid.

Thumbnail
Iron Oxidation

Ferric iron is an anaerobic terminal electron acceptor, with the final enzyme a ferric iron reductase.

Thumbnail
Nitrification

Nitrification is the process by which ammonia (NH3) or ammonium (NH4+) is converted to nitrite (NO2-) and then nitrate (NO3−) by bacteria.

Thumbnail
Anammox

Anammox, an abbreviation for ANaerobic AMMonium OXidation, is a globally significant microbial process of the nitrogen cycle.

Thumbnail
Benzoate Catabolism

Rhodobacter sphaeroides is able to produce hydrogen from a wide range of organic compounds (chiefly organic acids) and light.

Thumbnail
Polycyclic Aromatic Hydrocarbons

Polycyclic aromatic hydrocarbons are potent atmospheric pollutants that consist of fused aromatic rings and do not contain heteroatoms.

Section 11
Phototrophy
Thumbnail
The Purpose and Process of Photosynthesis

The process of photosynthesis converts light energy to chemical energy, which can be used by organisms for different metabolic processes.

Thumbnail
Main Structures and Summary of Photosynthesis

In multicellular autotrophs, the main cellular structures that allow photosynthesis to take place include chloroplasts, thylakoids, and chlorophyll.

Thumbnail
The Two Parts of Photosynthesis

Light-dependent and light-independent reactions are two successive reactions that occur during photosynthesis.

Thumbnail
Bacteriorhodopsin

Bacteriorhodopsin acts a proton pump, generating cellular energy in a manner independent of chlorophyll.

Thumbnail
Carotenoids and Phycobilins

To aid chlorophylls in the absorption of light not many photosynthetic organisms use carotenoids and phycobilins.

Thumbnail
Facultative Phototrophy

A facultative phototroph can rely on photosynthesis and alternative energy sources to survive and grow.

Thumbnail
Oxygenic Photosynthesis

Oxygenic photosynthesis, provides energy to organism and allows for carbon fixation, all the while producing oxygen as a byproduct.

Thumbnail
Anoxygenic Photosynthesis

Photosynthetic reactions can be anoxygenic, thus they do not produce oxygen.

Section 12
Biosynthesis
Thumbnail
Substrates for Biosynthesis

Major metabolic pathways require substrates to be acted upon for the formation of larger, more complex products.

Thumbnail
Biosynthesis and Energy

Biosynthetic processes ensure the production of complex products necessary for cellular and metabolic processes.

Thumbnail
The Calvin Cycle

The Calvin cycle is organized into three basic stages: fixation, reduction, and regeneration.

Thumbnail
Intermediates Produced During the Calvin Cycle

The Calvin Cycle involves the process of carbon fixation to produce organic compounds necessary for metabolic processes.

Thumbnail
Regulation of the Calvin Cycle

The Calvin cycle is a process that ensures carbon dioxide fixation in plants.

Thumbnail
The Reverse TCA Cycle

The reverse TCA cycle utilizes carbon dioxide and water to form carbon compounds.

Thumbnail
The Acetyl-CoA Pathway

The acetyl-CoA pathway utilizes carbon dioxide as a carbon source and often times, hydrogen as an electron donor to produce acetyl-CoA.

Thumbnail
The 3-Hydroxypropionate Cycle

The 3-hydroxypropionate cycle is a carbon fixation pathway that results in the production of acetyl-CoA and glyoxylate.

Section 13
Anabolism
Thumbnail
Polysaccharide Biosynthesis

Polysaccharides are synthesized from two forms of activated glucose molecules: UDP-glucose and ADP-glucose.

Thumbnail
Lipid Biosynthesis

Many of the immune activating abilities of lipopolysaccharide can be attributed to the lipid A unit.

Thumbnail
Regulation by Biosynthetic Enzymes

Attenuation is a regulatory feature found throughout Archaea and Bacteria domains which causes premature termination of transcription.

Thumbnail
Bacterial Polyesters

Polyhydroxyalkanoates or PHAs are linear polyesters produced in nature by bacterial fermentation of sugar or lipids.

Thumbnail
Polyketide Antibiotics

Polyketides are secondary metabolites produced from bacteria, fungi, plants, and animals.

Section 14
Amino Acid and Nucleotide Biosynthesis
Thumbnail
Amino Acid Synthesis

Organisms vary in their ability to synthesize the 20 common amino acids, but most bacteria and plants can synthesize all 20.

Thumbnail
Purine and Pyrimidine Synthesis

Unlike pyrimidines, purines are biologically synthesized as nucleotides and in particular as ribotides.

Thumbnail
Nonribosomal Peptide Antibiotics

Nonribosomal peptides (NRP) are a class of peptide secondary metabolites which can function as antibiotics.

Thumbnail
Biosynthesis of Tetrapyrroles

Porphyrins are the conjugate acids of ligands that bind metals to form complexes.

Section 15
Nitrogen Fixation
Thumbnail
Nitrogenase and Nitrogen Fixation

The process of nitrogen fixation is carried out in microbes.

Thumbnail
Early Discoveries in Nitrogen Fixation

Nitrogen fixation carried out by bacteria helps farmers yield healthy crops.

Thumbnail
Nitrogen Fixation Mechanism

The conversion of N2 to NH3 depends on a complex reaction, essential to which are enzymes known as nitrogenases.

Thumbnail
Anaerobiosis and N2 Fixation

Nitrogen fixing bacteria have different strategies to reduce oxygen levels, which interfere with nitrogenase function.

Thumbnail
Genetics and Regulation of N2 Fixation

Through control of gene expression, nitrogen fixing bacteria can turn on and off the proteins needed for nitrogen fixation.

You are in this book
Boundless Microbiology by Boundless
Previous Chapter
Chapter 4
Cell Structure of Bacteria, Archaea, and Eukaryotes
  • Overview of Prokaryotic and Eukaryotic Cells
  • The Cytoplasmic Membrane of Prokaryotic and Eukaryotic Cells
  • Transport Across the Cell Membrane
  • Cell Walls of Prokaryotes
  • Specialized External Structures of Prokaryotes
and 5 more sections...
Current Chapter
Chapter 5
Microbial Metabolism
  • Types of Metabolism
  • Energy Production
  • Catabolism
  • Glycolysis
  • Respiratory ETS and ATP Synthase
and 10 more sections...
Next Chapter
Chapter 6
Culturing Microorganisms
  • Microbial Nutrition
  • Cell Differentiation and Starvation
  • Culturing Bacteria
  • Microbial Culture Methods
  • Bacterial Identification
and 10 more sections...
Subjects
  • Accounting
  • Algebra
  • Art History
  • Biology
  • Business
  • Calculus
  • Chemistry
  • Communications
  • Economics
  • Finance
  • Management
  • Marketing
  • Microbiology
  • Physics
  • Physiology
  • Political Science
  • Psychology
  • Sociology
  • Statistics
  • U.S. History
  • World History
  • Writing

Except where noted, content and user contributions on this site are licensed under CC BY-SA 4.0 with attribution required.