mesenchyme

Examples of mesenchyme in the following topics:

• Development of Vision

  • The eye forms from the neural tube, epidermis, and the periocular mesenchyme, with sequential inductions of tissue during development.
  • The eye develops from the neural tube, the epidermis, and the periocular mesenchyme, which receives contributions from both the neural crest and mesoderm lineages.
  • Periocular mesenchyme: The periocular mesenchyme migrates inward during the formation of the optic cup.
  • The mesenchyme contributes to the cornea, iris, ciliary body, sclera, and blood vessels of the eye.

• Embryonic and Fetal Bone Formation

  • Embryonic mesenchymal cells (MSC) condense into layers of vascularized primitive connective tissue.
  • Certain mesenchymal cells group together, usually near or around blood vessels, and differentiate into osteogenic cells that deposit bone matrix constitutively.
  • Separate mesenchymal cells differentiate into osteoblasts, which line up along the surface of the spicule and secrete more osteoid, increasing the size of the spicule.

• Cartilage Growth

  • Chondrification is the process by which cartilage is formed from condensed mesenchyme tissue.
  • Chondrification (also known as chondrogenesis) is the process by which cartilage is formed from condensed mesenchyme tissue.
  • Mesenchyme tissue differentiates into chondroblasts and begins secreting the molecules that form the extracellular matrix (ECM).
  • Mesenchymal stem cells (MSCs) are undifferentiated, meaning they can give rise to different cell types.

• Lymphatic Tissue Development

  • With the exception of the anterior part of the sac from which the cisterna chyli develops, all lymph sacs become invaded by mesenchymal cells and are converted into groups of lymph nodes .
  • The spleen develops from mesenchymal cells between layers of the dorsal mesentery of the stomach.

• Gastrulation

  • Cells from the epiblast at the primitive streak undergo an epithelial to mesenchymal transition and ingress at the primitive streak to form the germ layers.
  • Following gastrulation, the cells in the body are either organized into sheets of connected cells (as in epithelia), or as a mesh of isolated cells, such as mesenchyme.

• Development of the Urinary System

  • Intermediate mesenchyme or intermediate mesoderm is a type of embryological tissue called "mesoderm" that is located between the paraxial mesoderm and the lateral plate.

• Fontanels

  • The mesenchymal connective tissue turns into bone tissue.

• Development of the Extraembryonic Coelom

  • During the formation of the primitive yolk sac, some of the migrating hypoblast cells transdifferentiate into mesenchymal cells that fill the space between Heuser's membrane and the trophoblast to form the extra-embryonic mesoderm.

• Yolk Sac Development

  • The yolk sac, situated on the ventral aspect of the embryo, is lined by extra-embryonic endoderm, outside of which is a layer of extra-embryonic mesenchyme derived from the mesoderm.

• Development of the Peripheral Nervous System

  • Subsequently, neural crest cells from the roof plate of the neural tube undergo an epithelial to mesenchymal transition, delaminating from the neuroepithelium and migrating through the periphery where they differentiate into varied cell types, including pigment cells and the cells of the PNS.