Development of microbial resistance to antimicrobial agents requires alterations in the microbe's cell physiology and structure.
Antibiotic misuse is one factor responsible for the emergence of antimicrobial resistant bacterial strains.
Antimicrobial resistance is a major public health and economic burden on patients, affected communities, and healthcare providers.
Biofilms and persisters are bacterial communities responsible for chronic diseases and antibiotic tolerance.
Antimicrobial resistance has created a public health crisis in the treatment of infectious diseases and necessitates the discovery of new drugs.
Antimicrobial peptides exhibit cytotoxic activity against all microbes.
Antisense agents are short oligonucleotides that bind to target messenger RNA and inhibit protein synthesis.