CMV retinitis

(noun)

An inflammation of the eye's retina caused by CMV. It can lead to blindness.

Examples of CMV retinitis in the following topics:

  • Antiviral DNA Synthesis Inhibitors

    • It is also used to treat cytomegalovirus infection (CMV) and specifically CMV retinitis.
  • Other Infectious Eye Diseases

    • Cytomegalovirus retinitis, also known as CMV retinitis, is an inflammation of the retina of the eye that can lead to blindness.
  • Cytomegalovirus Infections

    • Cytomegalovirus (CMV) is a type of herpesvirus that largely affects infants and the immunocompromised.
    • Cytomegalovirus (CMV) is a viral genus of the viral family known as Herpesviridae or herpesviruses.
    • CMV, like all herpesviruses, can stay latent for long durations of time.
    • Transplant patients with CMV are also susceptible to pneumonia and hepatitis.
    • A vaccine against (CMV) is currently under investigation.
  • The TORCH Panel of Tests

    • Hematoxylin and Eosin stain showing cytomegalovirus (CMV) infection of the placenta (CMV placentitis), a TORCH infection.
    • The characteristic large nucleus of a CMV infected cell is seen off-center at the bottom-right of the image.
  • Transduction of Light

    • When light hits a photoreceptor, it causes a shape change in the retinal, altering its structure from a bent (cis) form of the molecule to its linear (trans) isomer.
    • This isomerization of retinal activates the rhodopsin, starting a cascade of events that ends with the closing of Na+ channels in the membrane of the photoreceptor.
    • Thus, the visual system relies on changein retinal activity, rather than the absence or presence of activity, to encode visual signals for the brain.
    • (a) Rhodopsin, the photoreceptor in vertebrates, has two parts: the trans-membrane protein opsin and retinal.
    • When light strikes the retinal, it changes shape from (b) a cis to a trans form.
  • Bacteriorhodopsin

    • Each chain has seven transmembrane alpha helices and contains one molecule of retinal buried deep within, the typical structure for retinylidene proteins.
    • It is the retinal molecule that changes its conformation when absorbing a photon, resulting in a conformational change of the surrounding protein and the proton pumping action.
    • Reprotonation of the retinal molecule by restores its original isomerized form.
  • Magnification and Resolution

    • The labels represent various parts of the human eye: Bruch membrane (B); choroid (C); retinal pigment epithelium (RPE); and retinal rod cells (R).
  • Perceiving Motion

    • Motion is perceived when two different retinal pathways, which rely on specific features and luminance, converge together.
  • Development of Vision

    • The optic cup then delaminates into two layers: the neural retina and the retinal pigment epithelium.
    • The periocular mesenchyme migrates inward during the formation of the optic cup and is critical for the induction of the retinal pigment epithelium and the optic nerve.
  • Viral Pneumonia

    • Viruses that primarily cause other diseases, but sometimes cause pneumonia, include herpes simplex virus (HSV, mainly in newborns), varicella-zoster virus (VZV), measles virus, rubella virus, and cytomegalovirus (CMV, mainly in people with immune system problems).
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