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Registry of Toxic Effects of Chemical Substances (RTECS)

Uranium

RTECS #

YR3490000

CAS #

7440-61-1; 24678-82-8

Updated

September 201

Molecular Weight

238.00

Molecular Formula

U

Synonyms

Uranium (ACGIH:OSHA)

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
unreported route/rat lethal dose (50 percent kill): 750 mg/kgGISAAA 37(10),27,1972

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/rat lowest published toxic dose: 121.635 mg/kg/6W- continuousBehavioral: Sleep

Behavioral: Change in psychophysiological tests		NETOX* 26,1015,2005

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.2 mg/m3;short term exposure limit 0.6 mg/m3DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Confirmed human carcinogenDTLVS* TLV/BEI,2013
TOXICOLOGY REVIEWMUREAV 566,21,2004
TOXICOLOGY REVIEWHXPHAU 36,165,1973
TOXICOLOGY REVIEWAJMEAZ 38,409,1965
TOXICOLOGY REVIEWDIMON* 46,551,2000
TOXICOLOGY REVIEWENTOX* -,406,2005
TOXICOLOGY REVIEWJTEHD6 7,297,2004
TOXICOLOGY REVIEWMUREAV 544,273,2003
TOXICOLOGY REVIEWHBTME* ,881,2007
TOXICOLOGY REVIEWHTOPA* 1,701,2002

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 0.2 mg/m3DTLVS* 3,274,1971
Occupational Exposure Limit-AUSTRALIAtime-weighted average 0.2 mg/m3, short term exposure limit 0.6 mg/m3, JUL2008
Occupational Exposure Limit-BELGIUMtime-weighted average 0.2 mg/m3, short term exposure limit 0.6 mg/m3, MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 0.2 mg(U)/m3, MAY2011
Occupational Exposure Limit-ICELANDtime-weighted average 0.2 mg/m3, NOV2011
Occupational Exposure Limit-KOREAtime-weighted average 0.2 mg/m3, short term exposure limit 0.6 mg/m3, 2006
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 0.2 mg/m3, carcinogen, JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 0.2 mg/m3, JAN1999
Occupational Exposure Limit-PERUtime-weighted average 0,2 mg/m3; short term exposure limit 0,6 mg/m3, JUL2005
Occupational Exposure Limit-POLANDMAC(time-weighted average) 0.015 mg/m3, MAC(short term exposure limit) 0.12 mg/m3, JAN1999
Occupational Exposure Limit-POLANDMAC(time-weighted average) 0.075 mg/m3, JAN1993
Occupational Exposure Limit-RUSSIAshort term exposure limit 0.075 mg(U)/m3, JUN2003
Occupational Exposure Limit-SWITZERLANDMAK-week 0.2 mg/m3, inhal, JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 0.2 mg/m3, 2003
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 0.25 mg/m3, JAN1993
Occupational Exposure Limit-TURKEYtime-weighted average 0.05 mg/m3, JAN1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 0.25 mg(U)/m3CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 0.25 mg(U)/m3CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 0.05 mg(U)/m3CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 0.2 mg(U)/m3CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO URANIUM, insol-air10H Carcinogen time-weighted average 0.2 mg/m3;short term exposure limit 0.6 mg/m3NIOSH* DHHS #92-100,1992
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO URANIUM, soluble compounds-air10H Carcinogen time-weighted average 0.05 mg/m3NIOSH* DHHS #92-100,1992

Status in Federal Agencies

OrganizationReference
ATSDR TOXICOLOGY PROFILE (NTIS** PB/99/163362)
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
On EPA IRIS database

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