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Registry of Toxic Effects of Chemical Substances (RTECS)

Isopentyl alcohol, acetate

RTECS #

NS9800000

CAS #

123-92-2

Updated

September 201

Molecular Weight

130.21

Molecular Formula

C7H14O2

Synonyms

3-Methyl-1-butanol acetate
3-Methyl-1-butyl acetate
3-Methylbutyl acetate
3-Methylbutyl ethanoate
Acetic acid, isopentyl ester
Banana oil
Isoamyl acetate (ACGIH:OSHA)
Isoamyl ethanoate
Isoamylester kyseliny octove (Czech)
Isopentyl acetate
Pear oil

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/cat Lowest published lethal concentration: 35 gm/m3Behavioral: General anesthetic

Behavioral: Food intake (animal)

Kidney, Ureter, and Bladder: Proteinuria		AGGHAR 5,1,1933
oral/rabbit lethal dose (50 percent kill): 7422 mg/kgIMSUAI 41,31,1972
oral/rat lethal dose (50 percent kill): 16600 mg/kgYKYUA6 32,1241,1981
skin/rabbit lethal dose (50 percent kill): >5 gm/kgNTIS** OTS0573010
subcutaneous/guinea pig lowest published lethal dose: 5 gm/kgPeripheral Nerve and Sensation: Spastic paralysis with/without sensory change

Behavioral: General anesthetic		AGGHAR 5,1,1933

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 50 ppm;short term exposure limit 100 ppmDTLVS* TLV/BEI,2013

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 100 ppm (525 mg/m3)DTLVS* 3,138,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 50 ppm (270 mg/m3), short term exposure limit 100 ppm (541 mg/m3), JUL2008
Occupational Exposure Limit-BELGIUMtime-weighted average 50 ppm (270 mg/m3), short term exposure limit 100 ppm(540 mg/m3), MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 50 ppm (266 mg/m3), MAY2011
Occupational Exposure Limit-ECtime-weighted average 270 mg/m3 (50 ppm);short term exposure limit 540 mg/m3 (100 ppm), JUN2000
Occupational Exposure Limit-FRANCEVME 50 ppm (270 mg/m3), VLE 100 ppm (540 mg/m3), FEB2006
Occupational Exposure Limit-GERMANYMAK 50 ppm (270 mg/m3), 2011
Occupational Exposure Limit-HUNGARYtime-weighted average 270 mg/m3, short term exposure limit 540 mg/m3, SEP2000
Occupational Exposure Limit-ICELANDtime-weighted average 50 ppm (270 mg/m3), short term exposure limit 100 ppm (540 mg/m3), NOV2011
Occupational Exposure Limit-JAPANOccupational Exposure Limit 50 ppm (266.3 mg/m3), ceiling concentration 100 ppm (532.5 mg/m3), MAY2012
Occupational Exposure Limit-KOREAtime-weighted average 100 ppm (525 mg/m3), 2006
Occupational Exposure Limit-MEXICOtime-weighted average 100 ppm (525 mg/m3);short term exposure limit 125 ppm (655 mg/m3), 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 100 ppm (532 mg/m3), JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 50 ppm (260 mg/m3), JAN1999
Occupational Exposure Limit-PERUtime-weighted average 50 ppm (266 mg/m3); short term exposure limit 100 ppm (532 mg/m3), JUL2005
Occupational Exposure Limit-RUSSIAtime-weighted average 100 ppm, JUN2003
Occupational Exposure Limit-SWEDENtime-weighted average 100 ppm (500 mg/m3);short term exposure limit 150 ppm (800 mg/m3), JUN2005
Occupational Exposure Limit-SWITZERLANDMAK-week 50 ppm (260 mg/m3),KZG-week 50 ppm (260 mg/m3), JAN2011
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 100 ppm (525 mg/m3), JAN1993
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 50 ppm (270 mg/m3);short term exposure limit 100 ppm (541 mg/m3), OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 100 ppm (525 mg/m3)CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 100 ppm (525 mg/m3)CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 100 ppm (525 mg/m3)CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 100 ppm (525 mg/m3)CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO ISOAMYL ACETATE-air10H time-weighted average 100 ppmNIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code 40370; Number of Industries 62; Total Number of Facilities 7677; Number of Occupations 79; Total Number of Employees Exposed 97668; Total Number of Female Employees Exposed 32512
National Occupational Hazard Survey 1974Hazard Code 40370; Number of Industries 93; Total Number of Facilities 11016; Number of Occupations 75; Total Number of Employees Exposed 96405

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Esters I, 1450

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