Registry of Toxic Effects of Chemical Substances (RTECS)
Boron oxide
RTECS #
ED7900000CAS #
1303-86-2Updated
September 201Molecular Weight
69.62Molecular Formula
B2O3Synonyms
Boric anhydrideBoron oxide (ACGIH:OSHA)
Boron oxide, aerosol
Boron sesquioxide
Boron trioxide
Diboron trioxide
Fused boric acid
Skin and Eye Irritation and References
| Route/Organism | Dose | Effect | Reference | 
|---|---|---|---|
| eye /rabbit | 50 mg | AIHAAP 20,284,1959 | |
| skin /rabbit | 1 gm | AIHAAP 20,284,1959 | 
Acute Toxicity Data and References
| Route/Organism | Dose | Effect | Reference | 
|---|---|---|---|
| inhalation/rat | Lowest published lethal concentration: 150 mg/m3/2H | VCVN1* -,193,1988 | |
| intraperitoneal/mouse | lethal dose (50 percent kill): 1868 mg/kg | VCVN1* -,193,1988 | |
| oral/mouse | lethal dose (50 percent kill): 3163 mg/kg | VCVN1* -,193,1988 | |
| oral/rat | lethal dose (50 percent kill): 3150 mg/kg | VCVN1* -,193,1988 | 
Other Multiple Dose Data and References
| Route/Organism | Dose | Effect | Reference | 
|---|---|---|---|
| inhalation/Dog | lowest published toxic concentration: 57 mg/m3/23W- intermittent | Kidney, Ureter, and Bladder: Other changes in urine composition Kidney, Ureter, and Bladder: Incontinence | VCVN1* -,194,1988 | 
| inhalation/rat | lowest published toxic concentration: 77 mg/m3/6H/24W- intermittent | Kidney, Ureter, and Bladder: Urine volume increased Kidney, Ureter, and Bladder: Other changes in urine composition | AIHAAP 20,284,1959 | 
| inhalation/rat | lowest published toxic concentration: 150 mg/m3/2H/15D- intermittent | Olfaction: Other olfaction effects Lung, Thorax, or Respiration: Other changes Nutritional and Gross Metabolic: Weight loss or decreased weight gain | VCVN1* -,194,1988 | 
| inhalation/rat | lowest published toxic concentration: 470 mg/m3/24W- intermittent | Kidney, Ureter, and Bladder: Other changes in urine composition Kidney, Ureter, and Bladder: Incontinence | VCVN1* -,194,1988 | 
Reviews
| Organization | Standard | Reference | 
|---|---|---|
| American Conference of Governmental Industrial Hygienists (ACGIH) | Threshold Limit Value-time-weighted average 10 mg/m3 | DTLVS* TLV/BEI,2013 | 
Standards and Regulations
| Organization | Standard | Reference | 
|---|---|---|
| Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION | FEREAC 54,7740,1989 | |
| Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES | RED Completed | RBREV* -,91,1998 | 
| Mine Safety and Health Administration (MSHA) STANDARD-air | time-weighted average 10 mg/m3 | DTLVS* 3,26,1971 | 
| Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV; | ||
| Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV | ||
| Occupational Exposure Limit-AUSTRALIA | time-weighted average 10 mg/m3, JUL2008 | |
| Occupational Exposure Limit-AUSTRIA | MAK-TMW 15 mg/m3;KZW 75 mg/m3, inhal, 2007 | |
| Occupational Exposure Limit-BELGIUM | time-weighted average 10 mg/m3, MAR2002 | |
| Occupational Exposure Limit-DENMARK | time-weighted average 10 mg/m3, MAY2011 | |
| Occupational Exposure Limit-FRANCE | VME 10 mg/m3, FEB2006 | |
| Occupational Exposure Limit-ICELAND | time-weighted average 10 mg/m3, NOV2011 | |
| Occupational Exposure Limit-KOREA | time-weighted average 10 mg/m3, 2006 | |
| Occupational Exposure Limit-MEXICO | time-weighted average 10 mg/m3;short term exposure limit 20 mg/m3, 2004 | |
| Occupational Exposure Limit-NEW ZEALAND | time-weighted average 10 mg/m3, JAN2002 | |
| Occupational Exposure Limit-NORWAY | time-weighted average 10 mg/m3, JAN1999 | |
| Occupational Exposure Limit-PERU | time-weighted average 10 mg/m3, JUL2005 | |
| Occupational Exposure Limit-POLAND | MAC(time-weighted average) 10 mg/m3, JAN1999 | |
| Occupational Exposure Limit-RUSSIA | short term exposure limit 5 mg/m3, JUN2003 | |
| Occupational Exposure Limit-SWITZERLAND | MAK-week 10 mg/m3, inhal, JAN2011 | |
| Occupational Exposure Limit-THE NETHERLANDS | MAC-TGG 10 mg/m3, 2003 | |
| Occupational Exposure Limit-THE PHILIPPINES | time-weighted average 15 mg/m3, JAN1993 | |
| Occupational Exposure Limit-UNITED KINGDOM | time-weighted average 10 mg/m3;short term exposure limit 20 mg/m3, OCT2007 | |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) | 8H time-weighted average 15 mg/m3, total dust | CFRGBR 29,1926.55,1994 | 
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) | 8H time-weighted average 15 mg/m3 | CFRGBR 41,50-204.50,1994 | 
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) | 8H time-weighted average 15 mg/m3, total dust | CFRGBR 29,1910.1000,1994 | 
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) | 8H time-weighted average 15 mg/m3, total dust | CFRGBR 29,1915.1000,1993 | 
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) | 8H time-weighted average 5 mg/m3, respirable fraction | CFRGBR 29,1915.1000,1993 | 
NIOSH Documentation and Surveillance
| Organization | Standard | Reference | 
|---|---|---|
| National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO BORON OXIDE, total dust-air | 10H time-weighted average 10 mg/m3 | NIOSH* DHHS #92-100,1992 | 
| National Occupational Exposure Survey 1983 | Hazard Code 12963; Number of Industries 112; Total Number of Facilities 10437; Number of Occupations 78; Total Number of Employees Exposed 162342; Total Number of Female Employees Exposed 18457 | |
| National Occupational Hazard Survey 1974 | Hazard Code 12963; Number of Industries 69; Total Number of Facilities 2563; Number of Occupations 49; Total Number of Employees Exposed 15319 | 
Status in Federal Agencies
| Organization | Reference | 
|---|---|
| EPA TSCA Section 8(b) CHEMICAL INVENTORY | |
| EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001 | |
| On EPA IRIS database | 
- Page last reviewed:March 7, 2014
- Page last updated:February 6, 2017
- Content source:
									- National Institute for Occupational Safety and Health (NIOSH) Education and Information Division
 
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