Experimental Evolution and Selective Breeding
Experimental evolution is a field in evolutionary and experimental biology that is concerned with testing hypotheses and theories of evolution by using controlled experiments. Evolution may be observed in the laboratory as populations adapt to new environmental conditions and/or change by such stochastic processes as random genetic drift.
With modern molecular tools, it is possible to pinpoint the mutations that selection acts upon, what brought about the adaptations, and to find out how exactly these mutations work. Because of the large number of generations required for adaptation to occur, evolution experiments are typically carried out with microorganisms such as bacteria, yeast, or viruses.
History of Selective Breeding
Unwittingly, humans have carried out evolution experiments for as long as they have been domesticating plants and animals. Selective breeding of plants and animals has led to varieties that differ dramatically from their original wild-type ancestors. Examples are the cabbage varieties, maize, or the large number of different dog breeds .
Selective Breeding
This Chihuahua mix and Great Dane show the wide range of dog breed sizes created using artificial selection, or selective breeding.
One of the first to carry out a controlled evolution experiment was William Dallinger. In the late 19th century, he cultivated small unicellular organisms in a custom-built incubator over a time period of seven years (1880–1886). Dallinger slowly increased the temperature of the incubator from an initial 60 °F up to 158 °F. The early cultures had shown clear signs of distress at a temperature of 73 °F, and were certainly not capable of surviving at 158 °F. The organisms Dallinger had in his incubator at the end of the experiment, on the other hand, were perfectly fine at 158 °F. However, these organisms would no longer grow at the initial 60 °F. Dallinger concluded that he had found evidence for Darwinian adaptation in his incubator, and that the organisms had adapted to live in a high-temperature environment .
Dallinger Incubator
Drawing of the incubator used by Dallinger in his evolution experiments.
More recently, evolutionary biologists have realized that the key to successful experimentation lies in extensive parallel replication of evolving lineages as well as a larger number of generations of selection. For example, on February 15, 1988, Richard Lenski started a long-term evolution experiment with the bacterium E. coli. The experiment continues to this day, and is by now probably the largest controlled evolution experiment ever undertaken. Since the inception of the experiment, the bacteria have grown for more than 50,000 generations.