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Boundless Anatomy and Physiology
Physiology Textbooks Boundless Anatomy and Physiology
Physiology Textbooks
Physiology

Chapter 28

Reproduction, Chromosomes, and Meiosis

Book Version 29
By Boundless
Boundless Anatomy and Physiology
Physiology
by Boundless
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Section 1
The Link Between Genotype and Phenotype
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The Process and Purpose of Gene Expression Regulation

Gene expression is a highly complex, regulated process that begins with DNA transcribed into RNA, which is then translated into protein.

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The Relationship Between Genes and Proteins

Proteins, encoded by individual genes, orchestrate nearly every function of the cell.

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Chromosomal Theory of Inheritance

The Chromosomal Theory of Inheritance identified chromosomes as the genetic material responsible for Mendelian inheritance.

Section 2
Inherited Variation
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Advantages and Disadvantages of Sexual Reproduction

The genetic diversity of sexual reproduction, observed in most eukaryotes, is thought to give species better chances of survival.

Section 3
Chromosomal Behavior in Meiosis and Fertilization
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The Structure and Sequence of DNA

DNA is a double helix of two anti-parallel, complementary strands having a phosphate-sugar backbone with nitrogenous bases stacked inside.

Section 4
DNA
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DNA and RNA

DNA and RNA are nucleic acids that carry out cellular processes, especially the regulation and expression of genes.

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The DNA Double Helix

The DNA double helix looks like a twisted staircase, with the sugar and phosphate backbone surrounding complementary nitrogen bases.

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DNA Packaging

DNA packaging is an important process in living cells. Without it, a cell is not able to accommodate the large amount of DNA that is stored inside.

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Types of RNA

RNA is the nucleic acid that makes proteins from the code provided by DNA through the processes of transcription and translation.

Section 5
Cell Division
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The Role of the Cell Cycle

The cell cycle allows multiicellular organisms to grow and divide and single-celled organisms to reproduce.

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Genomic DNA and Chromosomes

The genome of an organism consists of its entire complement of DNA, which encodes the genes that control the organism's characteristics.

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Eukaryotic Chromosomal Structure and Compaction

Chromosomes must coil to pack DNA into the cell during cell division, a process involving 3 levels of compaction.

Section 6
Sources of Genetic Variation
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Genetic Variation

Genetic variation is a measure of the variation that exists in the genetic makeup of individuals within population.

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Mendel's Law of Segregation

Mendel's Law of Segregation states that a diploid organism passes a randomly selected allele for a trait to its offspring, such that the offspring receives one allele from each parent.

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Mendel's Law of Independent Assortment

Independent assortment allows the calculation of genotypic and phenotypic ratios based on the probability of individual gene combinations.

Section 7
Complex Inheritance Patterns
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The Punnett Square Approach for a Monohybrid Cross

A Punnett square applies the rules of probability to predict the possible outcomes of a monohybrid cross and their expected frequencies.

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Phenotypes and Genotypes

The observable traits expressed by an organism are referred to as its phenotype and its underlying genetic makeup is called its genotype.

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Mendel’s Model System

The garden pea has several advantageous characteristics that allowed Mendel to develop the laws of modern genetics.

Section 8
Patterns of Inheritance
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Lethal Inheritance Patterns

Inheriting two copies of mutated genes that are nonfunctional can have lethal consequences.

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Sex-Linked Traits

A gene present on one of the sex chromosomes (X or Y in mammals) is a sex-linked trait because its expression depends on the sex of the individual. 

Section 9
Genetic Disequilibrium
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Genetic Linkage and Distances

Linked genes can become unlinked during recombination; the probability of genes separating depends on their distance from each other.

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Chromosomal Structural Rearrangements

Structural rearrangements of chromosomes include both inversions and translocations, which may have detrimental effects on an organism.

Section 10
Exceptions to Mendelian Inheritance
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Mendel's Laws of Heredity

Mendel formed the Laws of Heredity (the Law of Segregation and the Law of Independent Assortment) from his pea plant experiments.

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Boundless Anatomy and Physiology by Boundless
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Human Development and Pregnancy
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  • First Week of Development
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Chapter 28
Reproduction, Chromosomes, and Meiosis
  • The Link Between Genotype and Phenotype
  • Inherited Variation
  • Chromosomal Behavior in Meiosis and Fertilization
  • DNA
  • Cell Division
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APPENDIX A: Diseases, Injuries, and Disorders of the Organ Systems
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