trophoblast

(noun)

The membrane of cells that forms the wall of a blastocyst during early pregnancy, and also provides nutrients to the embryo and later develops into part of the placenta.

Related Terms

  • morula
  • zygote
  • cleavage
  • endometrium
  • human chorionic gonadotropin (hCG)
  • extravillous trophoblast
  • decidualization
  • implantation

(noun)

The membrane of cells that forms the wall of a blastocyst during early pregnancy and provides nutrients to the embryo and later develops into part of the placenta.

Related Terms

  • morula
  • zygote
  • cleavage
  • endometrium
  • human chorionic gonadotropin (hCG)
  • extravillous trophoblast
  • decidualization
  • implantation

Examples of trophoblast in the following topics:

  • Trophoblast Development

    • Trophoblasts are the outer layer of cells that provide nutrients to the embryo and form part of the placenta.
    • This layer of trophoblasts is also collectively referred to as the trophoblast, or, after gastrulation, the trophectoderm, as it is then contiguous with the ectoderm of the embryo.
    • Cytotrophoblast in the tips of villi can differentiate into another type of trophoblast called the extravillous trophoblast.
    • Extravillous trophoblasts grow out from the placenta and penetrate into the decidualized uterus.
    • Trophoblast., u.e.
  • Development of the Extraembryonic Coelom

    • It is located between Heuser's membrane and the trophoblast.
    • The extra-embryonic coelom (or chorionic cavity) is a portion of the conceptus consisting of a cavity between Heuser's membrane and the trophoblast.
    • The chorionic plate is composed of an inner layer of somatopleuric mesoderm and an outer layer of trophoblast cells.
    • It consists of an extra-embryonic mesoderm and two layers of trophoblast and surrounds the embryo and other membranes.
    • Chorionic villi are at first small and nonvascular, and consist of only trophoblast, but they increase in size and branch.
  • Blastocyst Formation

    • The blastocyst possesses an inner cell mass (ICM), or embryoblast, which subsequently forms the embryo, and an outer layer of cells, or trophoblast, which later forms the placenta.
    • The trophoblast surrounds the inner cell mass and a fluid-filled, blastocyst cavity known as the blastocoele or the blastocystic cavity.
    • The trophoblast combines with the maternal endometrium to form the placenta in eutherian mammals.
    • Before gastrulation, the cells of the trophoblast become differentiated into two strata.
    • The blastocyst possesses an inner cell mass from which the embryo will develop, and an outer layer of cells, called the trophoblast, which will eventually form the placenta.
  • Implantation

    • The zona pellucida degenerates and decomposes, and is replaced by a layer of underlying cells called the trophoblast.
    • The trophoblast will give rise to the placenta after implantation.
    • During implantation, the trophoblast differentiates into two distinct layers: the inner cytotrophoblast, and the outer syncytiotrophoblast.
    • During implantation, extensions of the trophoblast, the syncytiotrophoblasts, embed within the endometrium and form chorionic villi.
  • Cleavage of the Zygote

    • However, they quickly become arranged into an outer or peripheral layer, the trophoblast, and an inner cell mass.
    • The trophoblast does not contribute to the formation of the embryo proper; the embryo develops from the inner cell mass .
    • Fluid collects between the trophoblast and the greater part of the inner cell mass, and thus the morula, is converted into the blastodermic vesicle (also called the blastocyst or blastula).
    • The inner cell mass remains in contact with the trophoblast at one pole of the ovum.
  • Chorionic Villi and Placental Development

    • During the primary stage (the end of fourth week), the chorionic villi are small, nonvascular, and contain only the trophoblast.
    • During the secondary stage (the fifth week), the villi increase in size and ramify, while the mesoderm grows into them; at this point the villi contain trophoblast and mesoderm.
    • At this point, the villi contain trophoblast, mesoderm, and blood vessels.
    • The outer layer of the blastocyst becomes the trophoblast, which forms the outer layer of the placenta.
  • Sinusoid Development

    • The invasion of endometrial sinusoids by the trophoblast allows maternal blood flow into the trophoblastic lacunae; this forms the uteroplacental blood circulation.
  • Fourth Week of Development

    • Trophoblast cells surrounding the embryonic cells proliferate and invade deeper into the uterine lining.
  • Early Pregnancy Tests

    • The first of these markers to be discovered, human chorionic gonadotropin (hCG), is produced by the trophoblast cells of the fertilized ovum (blastocyst).
  • Tissue Development

    • This then becomes a blastocyst, consisting of an outer layer called a trophoblast, and an inner cell mass called the embryoblast.
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