Luteinizing hormone

(noun)

A hormone produced by gonadotropic cells of the anterior pituitary gland. It triggers ovulation and development of the corpus luteum in females and stimulates Leydig cell production of testosterone in males.

Related Terms

  • sertoli cells
  • follicle-stimulating hormone
  • testes
  • Leydig cells
  • testicle

Examples of Luteinizing hormone in the following topics:

  • Hormonal Regulation of the Male Reproductive System

    • Hormonal control of spermatogenesis varies among species.
    • They are capable of producing the hormones estradiol and inhibin.
    • There it stimulates the synthesis and secretion of the gonadotropins, FSH and luteinizing hormone (LH).
    • Follicle-stimulating hormone (FSH)  is released by the anterior pituitary gland.
    • Luteinizing hormone (LH) is released by the anterior pituitary gland.
  • Onset, Duration, and Half-Life of Hormone Activity

    • A hormone's half-life and duration of activity are limited and vary from hormone to hormone.
    • A hormone's half-life and duration of activity are limited and vary from hormone to hormone.
    • For instance, the biological half-life of luteinizing hormone is 20 minutes, which is shorter than that of a follicle-stimulating hormone (three to four hours), and of human chorionic gonadotropin (24 hours).
    • Follicle-stimulating hormone 2.
    • Luteinizing hormone 4.
  • Hormonal Regulation of the Female Reproductive Cycle

    • The menstrual cycle is controlled by a series of changes in hormone levels, primarily estrogen and progesterone.
    • Follicle-stimulating hormone (FSH) is secreted by the anterior pituitary gland.
    • Follicle-stimulating hormone induces the proliferation of granulosa cells in the developing follicles and the expression of luteinizing hormone (LH) receptors on these cells.
    • Luteinizing hormone induces androgen synthesis by theca cells, stimulates proliferation, differentiation, and increases LH receptor expression on granulosa cells.
    • The surge also initiates luteinization of theca and granulosa cells.
  • Oogenesis

    • At the start of the menstrual cycle, some 12-20 primary follicles begin to develop under the influence of elevated levels of follicle-stimulating hormone (FSH) to form secondary follicles.
    • On day 14 of the cycle, a luteinizing hormone surge is triggered by the positive feedback of estrogen.
    • Differentiate among the stages of oogenesis and the actions of hormones during each stage
  • The Anterior Pituitary

    • Thyroid-stimulating hormone is a glycoprotein hormone that affects the thyroid gland and the secretion of thyroid hormones.
    • Follicle-stimulating hormone is a glycoprotein hormone that targets the gonads and effects the growth of the reproductive system.
    • Luteinizing hormone is a glycoprotein hormone that targets the gonads to effect sex-hormone production.
    • Growth hormone is a polypeptide hormone that targets the liver and adipose tissue and promotes growth through lipid and carbohydrate metabolism.
    • Hormone secretion from the anterior pituitary gland is regulated by hormones secreted by the hypothalamus.
  • Hormone Receptors

    • A hormone receptor is a molecule that binds to a specific hormone.
    • Receptors for peptide hormones tend to be found on the plasma membrane of cells, whereas receptors for lipid-soluble hormones are usually found within the cytoplasm.
    • The hormone activity within a target cell is dependent on the effective concentration of hormone-receptor complexes that are formed.
    • Many hormones are composed of polypeptides—such as thyroid-stimulating hormones, follicle-stimulating hormones, luteinizing hormones, and insulin.
    • Lipophilic hormones—such as steroid or thyroid hormones—are able to pass through the cell and nuclear membrane; therefore receptors for these hormones do not need to be, although they sometimes are, located in the cell membrane.
  • Uterine (Menstrual) Cycle

    • The discharge of blood slows and then stops in response to rising hormone levels, and the lining of the uterus thickens, or proliferates, hence the name of the phase.
    • Ovulation is triggered by a surge in luteinizing hormone.
    • The sudden change in hormones at the time of ovulation sometimes causes minor changes in the endometrium and light mid-cycle blood flow.
    • These hormone drops cause the uterus to shed its lining and the egg in a process termed menstruation.
  • Male and Female Gonads

    • Prior to ovulation, follicle-stimulating hormone is secreted by the granulosal cells that convert testosterone into estradiol.
    • The functions of the testicles are influenced by gonadotropic hormones, that are produced by the anterior pituitary.
    • Luteinizing hormone results in testosterone release.
    • The presence of both testosterone and follicle-stimulating hormone is needed to support spermatogenesis.
  • Hormonal Methods

    • Hormonal birth control contains steroid hormones that alter female fertility.
    • Altogether, 18% of the world's contraceptive users rely on hormonal methods.
    • Hormonal contraception is highly effective: when taken on the prescribed schedule, users of steroid hormone methods experience pregnancy rates of less than 1% per year.
    • The effect of hormonal agents on the reproductive system is complex.
    • Progesterone negative feedback decreases the frequency of gonadotropin-releasing hormone (GnRH) released by the hypothalamus, which decreases the release of follicle-stimulating hormone (FSH), and greatly decreases the release of luteinizing hormone (LH) by the anterior pituitary.
  • Puberty

    • It is initiated by hormonal signals from the brain to the gonads; the ovaries in a girl, the testes in a boy.
    • For boys, an androgen called testosterone is the principal sex hormone.
    • The hormone that dominates female development is an estrogen called estradiol.
    • Puberty, and sexual maturity thereafter, is regulated by a series of hormones and feedbacks in the body, illustrated here.
    • Hormones include: 1 Follicle-stimulating hormone - FSH. 2 Luteinizing hormone - LH. 3 Progesterone. 4 Estrogen. 5 Hypothalamus. 6 Pituitary gland. 7 Ovary. 8 Pregnancy - hCG (Human chorionic gonadotropin). 9 Testosterone. 10 Testicle. 11 Incentives. 12 Prolactin - PRL.
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