hair follicle

(noun)

The structure that produces hair.

Related Terms

  • papilla
  • hair fiber

Examples of hair follicle in the following topics:

  • Hair

    • The root is part of the hair enclosed by the hair follicle, which is itself a tube-like involution of the skin. 
    • An oval hair shaft is responsible for wavy hair. 
    • In the deepest portion of the each hair follicle lies the hair bulb. 
    • Depending on the kind of hair and location, hair can have one of several purposes:
    • Attached to a hair follicle is a bundle of muscle fibers. 
  • Chemotherapy and Hair Loss

    • Chemotherapy causes hair loss by killing cells that divide rapidly, one of the main properties of most cancer cells and hair follicles.
    • Chemotherapy also harms cells that divide rapidly under normal circumstances, such as cells in the bone marrow, mouth, nail beds, and hair follicles.
    • The hair of the scalp is most noticeably affected, but chemotherapy also causes the loss of the hair of the eyelashes, eyebrows, and the rest of the body.
    • Some chemotherapeutic agents cause dramatic hair loss and baldness, while other medications may only cause hair to thin .
    • Sometimes, a patient's hair will grow back differently.
  • Hair and Hormones

    • Male baldness is the result of genetic sensitivity of hair follicles to dihydrotestosterone that causes hair follicles to atrophy.
    • Male pattern baldness is caused by a genetic sensitivity of hair follicles to dihydrotestosterone (DHT).
    • In genetically-prone scalps, i.e. those experiencing male or female pattern baldness, DHT initiates a process of follicular miniaturization in which the hair follicle begins to deteriorate.
    • In time, hair becomes thinner and its overall volume is reduced, resembling fragile vellus hair or "peach fuzz" until, finally, the follicle falls dormant and ceases producing hair completely.
    • Recent research suggests that elevated levels of the enzyme prostaglandin D2 synthase and its product prostaglandin D2 (PGD2) in hair follicles contribute to androgenetic alopecia.
  • Sebaceous (Oil) Glands

    • Sebum acts to protect and waterproof hair and skin, and keep them from becoming dry, brittle, and cracked.
    • Sebum is the cause of some people experiencing "oily" hair if it is not washed for several days.
    • Sebaceous glands can usually be found in hair-covered areas where they are connected to hair follicles to deposit sebum on the hairs, and bring it to the skin surface along the hair shaft.
    • The structure consisting of hair, hair follicle, and sebaceous gland is also known as pilosebaceous unit.
    • Sebum is the cause of some people's experiencing "oily" hair, as in hot weather or if not washed for several days.
  • Acne

    • Acne, clinically known as acne vulgaris, is a common human skin disease affecting skin with the densest population of sebaceous follicles such as the face, upper parts of the chest, and back .
    • Acne develops as a result of blockages in hair follicles.
    • Bacteria becomes trapped in these clogged follicles, producing pus and inflammation as the immune system attempts to destroy the bacteria.
    • The sebaceous gland produces oily secretions that can block the follicle, resulting in a pimple.
  • Alopecia

    • Alopecia usually affects the hair of the scalp, but can also cause the loss of hair from the eyebrows, eyelashes, and body.
    • Alopecia areata is thought to be an autoimmune disorder in which the body attacks its own hair follicles and suppresses or stops hair growth.
    • Exclamation point hairs are often present in alopecia.
    • Exclamation point hairs are hairs that become narrower along the length of the strand closer to the base, producing a characteristic "exclamation point" appearance and weak point in the hair shaft.
    • Different skin areas can exhibit hair loss and regrowth at the same time.
  • Tactile Sensation

    • The hair cells in the cochlea are the most sensitive mechanoreceptors, transducing air pressure waves into nerve signals sent to the brain.
    • Hair follicle receptors are located in hair follicles and sense position changes of hair strands.
  • Hair Removal

    • Hair removal, also known as epilation or depilation, is the removal of body hair, and describes the methods used to achieve that result.
    • Although nearly all human skin is covered with hair follicles, it appears hairless.
    • Hair removal, also known as epilation or depilation, is the removal of body hair, and describes the methods used to achieve that result.
    • Depilation is the removal of the part of the hair above the surface of the skin.
    • Hair is also sometimes removed by plucking with tweezers.
  • Thermoregulation

    • The hairs on the skin lie flat and prevent heat from being trapped by the layer of still air between the hairs.
    • When these muscles relax their attached hair follicles are not erect.
    • In addition, our body thermoregulates using our hair. 
    • The arrector pili muscles contract (piloerection) and lift the hair follicles upright.
    • This makes the hairs stand on end, which acts as an insulating layer, trapping heat.
  • Oogenesis

    • Follicle development signals the beginning of the menstrual cycle.
    • At the start of the menstrual cycle, some 12-20 primary follicles begin to develop under the influence of elevated levels of follicle stimulating hormone (FSH) to form secondary follicles.
    • The primary follicles have formed from primordial follicles, which developed in the ovary as a fetus at around 10–30 weeks after conception and are arrested in the prophase state of the cellular cycle.
    • The remaining follicle is called the dominant follicle and is responsible for producing large amounts of estrogen during the late follicular phase.
    • This causes the secondary follicle to develop into a tertiary follicle, which then leaves the ovary 24–36 hours later.
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