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Mutation

The distribution of fitness effects

The distribution of fitness effects

The distribution of fitness effects of mutations in vesicular stomatitis virus. In this experiment, random mutations were introduced into the virus by site-directed mutagenesis. The fitness of each mutant was compared with the ancestral type. A fitness of zero, less than one, one, more than one, respectively, indicates that mutations are lethal, deleterious, neutral, and advantageous.

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    Boundless vets and curates high-quality, openly licensed content from around the Internet. This particular resource used the following sources:

    "DFE in VSV."
    http://en.wikipedia.org/wiki/File:DFE_in_VSV.png Wikipedia CC BY-SA.

Related Terms

  • mutation
  • site-directed mutagenesis
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