Microbiology
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Microbiology

Section 13

Bioinformatics

Book Version 6
By Boundless
Boundless Microbiology
Microbiology
by Boundless
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8 concepts
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Strategies Used in Sequencing Projects

The strategies used for sequencing genomes include the Sanger method, shotgun sequencing, pairwise end, and next-generation sequencing.

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Annotating Genomes

Genome annotation is the identification and understanding of the genetic elements of a sequenced genome.

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Homologs, Orthologs, and Paralogs

Homology describes the relationship between genes and how they are inherited from ancestors.

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Synthesizing DNA

DNA can be synthesized chemically for a number of purposes.

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Amplifying DNA: The Polymerase Chain Reaction

The polymerase chain reaction (PCR) is a method by which DNA is amplified.

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DNA Sequencing Based on Sanger Dideoxynucleotides

Sanger sequencing is based on the incorporation and detection of labeled ddNTPs as terminal nucleotides in DNA amplification.

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Metagenomics

Metagenomics is the study of genetic material derived from environmental samples.

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Reporter Fusions

A reporter fusion is the hybrid of a gene or portion of a gene with a tractable marker.

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