Microbiology
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Boundless Microbiology
Immunology Applications
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Microbiology

Section 2

Diagnostic Immunology

Book Version 6
By Boundless
Boundless Microbiology
Microbiology
by Boundless
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13 concepts
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Immunoassays for Disease

Immunoassays are laboratory techniques based on the detection of antibody production in response to foreign antigens.

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Antibody Functions

Antibodies, part of the humoral immune response, are involved in pathogen detection and neutralization.

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Serology

Serology is the study of blood serum and other bodily fluids for the identification of antibodies.

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Precipitation Reactions

Precipitation reactions are serological assays for the detection of immunoglobulin levels from the serum of a patient with infection.

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Agglutination Reactions

Agglutination reactions are used to assess the presence of antibodies in a specimen by mixing it with particulate antigens.

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Neutralization Reaction

Neutralization reactions are used to inactivate viruses and evaluate neutralizing antibodies.

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Complement Fixation

Complement fixation is a method that demonstrates antibody presence in patient serum.

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Fluorescent Antibodies

Fluorescent antibodies are antibodies that have been tagged with a fluorescent compound to facilitate their detection in the laboratory.

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Enzyme-Linked Immunosorbent Assay (ELISA)

Enzyme-linked immunosorbent assay (ELISA) is a solid-phase enzyme immunoassay used to detect the presence of a substance in solution.

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Immunoblot Procedures

Immunoblot is a technique for analyzing proteins via antigen-antibody specific reactions.

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Tests That Differentiate Between T Cells and B cells

Methods used to differentiate T cells and B cells include staining cell surface receptors and functional assays like the T lymphocyte cytotoxicity assay.

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In Vivo Testing

In vivo testing using animal models of disease help discover new ways of solving complex health problems.

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The Future of Diagnostic Immunology

The future of diagnostic immunology lies in the production of specific antibody-based assays and the development of improved vaccines.

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