sialic

(adjective)

Of or pertaining to sialic acid or its derivatives.

Related Terms

  • hemagglutinin
  • endosome
  • neuraminidase
  • glycoprotein

Examples of sialic in the following topics:

  • Attachment and Entry to the Host Cell

    • HA proteins bind to cells with sialic acid on the membranes, such as cells in the upper respiratory tract or erythrocytes.
    • First, it allows the recognition of target vertebrate cells, accomplished through the binding of these cells' sialic acid-containing receptors.
    • HA binds to the monosaccharide sialic acid that is present on the surface of its target cells, which causes the viral particles to stick to the cell's surface.
  • Replicative Cycle of Influenza A

    • Influenza viruses bind through hemagglutinin onto sialic acid sugars on the surfaces of epithelial cells, typically in the nose, throat, and lungs of mammals, and the intestines of birds (Step 1 in infection figure ).
    • As before, the viruses adhere to the cell through hemagglutinin; the mature viruses detach once their neuraminidase has cleaved sialic acid residues from the host cell.
  • Antiviral Agents that Prevent Virus Uncoating or Release

    • It cleaves sialic acid from glycoproteins on the surface of the host cell and allows the viral particles to leave the cell.
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