hemagglutinin

(noun)

An antigenic glycoprotein that causes agglutination of red blood cells.

Related Terms

  • sialic
  • neuraminidase

Examples of hemagglutinin in the following topics:

  • Replicative Cycle of Influenza A

    • After the hemagglutinin is cleaved by a protease, the cell imports the virus by endocytosis.
    • The hemagglutinin protein fuses the viral envelope with the vacuole's membrane.
    • Hemagglutinin and neuraminidase molecules cluster into a bulge in the cell membrane.
    • The mature virus buds off from the cell in a sphere of the host phospholipid membrane, acquiring hemagglutinin and neuraminidase with this membrane coat (Step 7).
    • Contrast the roles of hemagglutinin and neuraminidase throughout the major stages of the replicative cycle of influenza A virus
  • Attachment and Entry to the Host Cell

    • The glycoprotein responsible for attachment on the surface of an influenza viral particle is hemagglutinin (HA).
    • Of special note is HA (hemagglutinin), the glycoprotein critical for influenza attachment and entry into host cells.
    • Explain the role of hemagglutinin in the attachment and entry processes of influenza virus
  • Emergence of Viral Pathogens

    • For example, if a pig was infected with a human influenza virus and an avian influenza virus at the same time, an antigenic shift could occur, producing a new virus that had most of the genes from the human virus, but a hemagglutinin or neuraminidase from the avian virus.
    • The resulting new virus would likely be able to infect humans and spread from person to person, but it would have surface proteins (hemagglutinin and/or neuraminidase) not previously seen in influenza viruses that infect humans, and therefore most people would have little or no immune protection.
  • Coryza and Influenza

    • Hemagglutinin (HA) and neuraminidase (NA) are the two large glycoproteins on the outside of the viral particles.
  • Vaccines and Anti-Viral Drugs for Treatment

    • (b) Neuraminidase cleaves the connection between viral hemagglutinin (HA), also found in the viral envelope, and glycoproteins on the host cell surface.
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