sepsis

(noun)

A life-threatening medical condition caused by a severe inflammatory response of the human body triggered by the presence of an infectious agent.

Related Terms

  • septic shock
  • mortality rate

Examples of sepsis in the following topics:

  • Sepsis and Septic Shock

    • Sepsis is an illness in which the body has a severe response to bacteria or other germs.
    • A popular term for sepsis is blood poisoning.
    • In sepsis, blood pressure drops, resulting in septic shock.
    • If sepsis worsens to the point of end-organ dysfunction (renal failure, liver dysfunction, altered mental status, or heart damage) then the condition is called severe sepsis.
    • Compare and contrast the symptoms of: sepsis, severe sepsis, septic shock
  • Respiratory Distress Syndrome

    • ARDS can occur within 24 to 48 hours of an injury (trauma, burns, aspiration, massive blood transfusion, drug/alcohol abuse) or an acute illness (infectious pneumonia, sepsis, acute pancreatitis).
    • If the underlying disease or injurious factor is not removed, the amount of inflammatory mediators released by the lungs in ARDS may result in a systemic inflammatory response syndrome (or sepsis if there is lung infection).
    • The evolution towards shock and/or multiple organ failure follows paths analogous to the pathophysiology of sepsis.
    • The result is a critical illness in which the 'endothelial disease' of severe sepsis/SIRS is worsened by the pulmonary dysfunction, which further impairs oxygen delivery.
  • Pyelonephritis

    • Severe cases of pyelonephritis can lead to pyonephrosis (pus accumulation around the kidney), sepsis (a systemic inflammatory response of the body to infection), kidney failure and even death.
  • Prostatitis

    • Acute prostatitis is a serious condition that requires immediate treatment to prevent complications such as sepsis.
    • Severe infections may require hospitalization, while milder cases (no sepsis) can be treated with antibiotic administration combined with bed rest at home.
  • Fusobacteria

    • Lemierres's syndrome is also known as postanginal sepsis and is a form of thrombophlebitis.
  • Adjustments of the Infant at Birth

    • A positive airway pressure should be maintained and neonatal sepsis must be ruled out.
    • Similarly, excess substrate can also lead to problems, such as infant of a diabetic mother (IDM), hypothermia, or neonatal sepsis.
  • Group B Streptococcus Colonization

    • In newborns, the first symptoms are breathing difficulties and pneumonia, which can progress to meningitis and sepsis.
  • Medical Uses of Hematopoietic Growth Factors

    • Chemotherapy can cause myelosuppression and unacceptably low levels of white blood cells, making patients prone to infections and sepsis.
  • RBC Life Cycle

    • Many diseases that involve damage to RBCs (hemolytic anemias, sepsis, malaria, pernicious or nutritional anemias) or normal cellular processes that cause cellular damage (oxidative stress) may increase the rate of eryptosis.
  • Ecological Associations Among Microorganisms

    • Some organisms, such as Staphylococcus or Streptococcus, can cause skin infections, pneumonia, meningitis and even overwhelming sepsis, a systemic inflammatory response producing shock, massive vasodilation, and death.
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