sarcolemma

(noun)

The cell membrane of a myocyte.

Related Terms

  • motor-end plate
  • Sarcoplasm
  • sarcoplasm
  • sarcoplasmic reticulum
  • acetylcholinesterase
  • sarcomere
  • myofibril
  • myocyte

(noun)

a thin cell membrane that surrounds a striated muscle fiber

Related Terms

  • motor-end plate
  • Sarcoplasm
  • sarcoplasm
  • sarcoplasmic reticulum
  • acetylcholinesterase
  • sarcomere
  • myofibril
  • myocyte

Examples of sarcolemma in the following topics:

  • Excitation–Contraction Coupling

    • It is the link (transduction) between the action potential generated in the sarcolemma and the start of a muscle contraction .
    • The area of the sarcolemma on the muscle fiber that interacts with the neuron is called the motor-end plate.
    • The motor end plate possesses junctional folds: folds in the sarcolemma that create a large surface area for the neurotransmitter to bind to receptors.
    • The depolarization then spreads along the sarcolemma and down the T tubules, creating an action potential.
  • Skeletal Muscle Fibers

    • The sarcolemma of myocytes contains numerous invaginations (pits) called transverse tubules which are usually perpendicular to the length of the myocyte.
    • Myofibrils run parallel to the myocyte and typically run for its entire length, attaching to the sarcolemma at either end.
    • A skeletal muscle cell is surrounded by a plasma membrane called the sarcolemma with a cytoplasm called the sarcoplasm.
  • Muscle Development

    • These cells remain adjacent to a muscle fiber, situated between the sarcolemma and the endomysium (the connective tissue investment that divides the muscle fascicles into individual fibers).
    • Satellite cells are located between the basement membrane and sarcolemma (cell membrane) of individual muscle fibers.
  • Myocardial Thickness and Function

    • Each muscle fiber connects to the plasma membrane (sarcolemma) with distinctive tubules (T-tubule).
    • At these T-tubules, the sarcolemma is studded with a large number of calcium channels which allow calcium ion exchange, at a rate that occurs much faster compared to that of the neuromuscular junction in skeletal muscle.
  • Microscopic Anatomy

    • Sarcomeres are connected to a plasma membrane, called a sarcolemma, by T-tubules, which speed up the rate of depolarization within the sarcomere.
  • Short-Term Chemical Control

    • When stimulated a signal transduction cascade leads to increased intracellular calcium from the sarcoplasmic reticulum through IP3 mediated calcium release, as well as enhanced calcium entry across the sarcolemma through calcium channels.
  • Peripheral Motor Endings

    • Detailed view of a neuromuscular junction: (1) Presynaptic terminal; (2) Sarcolemma; (3) Synaptic vesicle; (4) Nicotinic acetylcholine receptor; (5) Mitochondrion.
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