occludin

Physiology

(noun)

A protein forming the main component of the tight junctions, along with the claudin group of proteins.

Related Terms

  • astrocyte
  • blood-brain barrier
  • claudins
Biology

(noun)

Together with the claudin group of proteins, it is the main component of the tight junctions.

Related Terms

  • plasmodesma
  • connexon

Examples of occludin in the following topics:

  • Tight Junctions

    • The occludins and claudins are the major components of tight junction strands.
    • Model of the protein structure of the coiled-coil domain of human occludin.
  • Intercellular Junctions

    • The cells are held tightly against each other by proteins (predominantly two proteins called claudins and occludins).
  • Blood-Brain Barrier

    • At the interface between blood and the brain, endothelial cells are joined by these tight junctions, which are composed of smaller subunits, frequently biochemical dimers that are transmembrane proteins such as occludin, claudins, and junctional adhesion molecule.
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