deamination

(noun)

The removal of an amino group from a compound.

Related Terms

  • keto acid
  • catabolism

Examples of deamination in the following topics:

  • Connecting Proteins to Glucose Metabolism

    • Each amino acid must have its amino group removed (deamination) prior to the carbon chain's entry into these pathways.
    • When deaminated, amino acids can enter the pathways of glucose metabolism as pyruvate, acetyl CoA, or several components of the citric acid cycle.
    • For example, deaminated asparagine and aspartate are converted into oxaloacetate and enter glucose catabolism in the citric acid cycle.
    • Deaminated amino acids can also be converted into another intermediate molecule before entering the pathways.
  • Tiffeneau-Demjanov Rearrangement

    • This uncertainty can be removed by nitrous acid deamination of the corresponding 1º-aminoalcohols, as shown in the following equation.
  • Absorptive State

    • The liver deaminates amino acids to keto acids to be used in the Kreb's cycle in order to generate energy in the form of ATP.
  • Types of Catabolism

    • The amino group is fed into the urea cycle, leaving a deaminated carbon skeleton in the form of a keto acid.
    • Several of these keto acids are intermediates in the citric acid cycle, for example the deamination of glutamate forms α-ketoglutarate.
  • Nanoarchaeum and Aciduliprofundum

    • It does have five subunits of an ATP synthase as well as pathways for oxidative deamination.
  • Biosynthesis of Tetrapyrroles

    • Four PBGs are then combined through deamination into hydroxymethyl bilane (HMB), which is hydrolysed to form the circular tetrapyrrole uroporphyrinogen III.
  • Type 1 Diabetes Mellitus

    • About a quarter of people with new type 1 diabetes have developed some degree of diabetic ketoacidosis (a type of metabolic acidosis which is caused by high concentrations of ketone bodies, formed by the breakdown of fatty acids and the deamination of amino acids) by the time the diabetes is recognized.
  • Rearrangements of Cationic or Electron Deficient Nitrogen

    • Acid-catalyzed addition of hydrazoic acid to the carbonyl group of a ketone creates an unstable azidocarbinol that, on dehydration, produces the same triazonium cation presumably formed as an intermediate in the nitrous acid deamination of a hydrazone.
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