common cause hypothesis

(noun)

Predicts that common disease-causing alleles, or variants, will be found in all human populations which manifest a given disease

Related Terms

  • autoimmune diseases

Examples of common cause hypothesis in the following topics:

  • Does the Difference Prove the Point?

    • Rejecting the null hypothesis does not necessarily prove the alternative hypothesis.
    • The critical region of a hypothesis test is the set of all outcomes which cause the null hypothesis to be rejected in favor of the alternative hypothesis.
    • Alternatively, if the testing procedure forces us to reject the null hypothesis ($H_0$), we can accept the alternative hypothesis ($H_1$) and we conclude that the research hypothesis is supported by the data.
    • Rejection of the null hypothesis is a conclusion.
    • We might accept the alternative hypothesis (and the research hypothesis).
  • Misconceptions

    • State why the probability value is not the probability the null hypothesis is false
    • Explain why a non-significant outcome does not mean the null hypothesis is probably true
    • Misconceptions about significance testing are common.
    • It is the probability of the data given the null hypothesis.
    • It is not the probability that the null hypothesis is false.
  • Type I and Type II Errors

    • The notion of statistical error is an integral part of hypothesis testing.
    • What we actually call type I or type II error depends directly on the null hypothesis, and negation of the null hypothesis causes type I and type II errors to switch roles.
    • A type I error occurs when the null hypothesis ($H_0$) is true but is rejected.
    • A common example is a guilty prisoner freed from jail.
    • A false positive (with null hypothesis of health) in medicine causes unnecessary worry or treatment, while a false negative gives the patient the dangerous illusion of good health and the patient might not get an available treatment.
  • Formulating the Hypothesis

    • A hypothesis is a potential answer to your research question; the research process helps you determine if your hypothesis is true.
    • This is an example of a causal hypothesis.
    • To test this hypothesis, he compared twenty different regional Italian governments.
    • While there is no single way to develop a hypothesis, a useful hypothesis will use deductive reasoning to make predictions that can be experimentally assessed.
    • In research, independent variables are the cause of the change.
  • Type I and II Errors

    • Explain why the null hypothesis should not be accepted when the effect is not significant
    • By one common convention, if the probability value is below 0.05, then the null hypothesis is rejected.
    • Another convention, although slightly less common, is to reject the null hypothesis if the probability value is below 0.01.
    • If the null hypothesis is false, then it is impossible to make a Type I error.
    • A Type II error can only occur if the null hypothesis is false.
  • Elements of a Hypothesis Test

    • The null hypothesis was that the Lady had no such ability.
    • Fisher asserted that no alternative hypothesis was (ever) required.
    • The typical line of reasoning in a hypothesis test is as follows:
    • Common values are 5% and 1%.
    • The former process was advantageous in the past when only tables of test statistics at common probability thresholds were available.
  • Prions

    • This is the central idea of the Prion Hypothesis, which remains debated.
    • All known mammalian prion diseases are caused by the so-called prion protein, PrP.
    • Fungal prions do not appear to cause disease in their hosts.
    • The virion hypothesis states that TSEs are caused by a replicable informational molecule (likely to be a nucleic acid) bound to PrP.
    • Compare the protein-only hypothesis of prion diseases with the virion hypothesis, as well as the heterodimer model and the fibril model of prion replication
  • Occurrence of a Disease

    • Develop a hypothesis (if there appears to be a cause for the outbreak).
    • Common source – All victims acquire the infection from the same source (e.g. a contaminated water supply).
    • Continuous source – Common source outbreak where the exposure occurs over multiple incubation periods.
    • Point source – Common source outbreak where the exposure occurs in less than one incubation period.
  • Psychology and the Scientific Method: From Theory to Conclusion

    • Descriptive studies describe the nature of the relationship between the intended variables, without looking at cause or effect.
    • Future testing may disprove the hypothesis.
    • Hypothesis testing is a type of statistics that determines the probability of a hypothesis being true or false.
    • If the hypothesis is false, create a new hypothesis or try again
    • After making a hypothesis, the researcher will then design an experiment to test his or her hypothesis and evaluate the data gathered.
  • Scientific Method - The Practice of Science

    • Simply put, it says look/listen, infer a cause and test your inference.
    • An hypothesis is a declarative sentence that sounds like a fact...but isn’t!
    • Design an experiment to test the hypothesis: results must be measurable evidence for or against the hypothesis.
    • Beyond these most common parts of the scientific method, most descriptions add two more precepts:
    • These Laws are thought of as universal and are most common in math and physics.
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