Claudins

(noun)

Proteins that form the backbone of the tight junction strands.

Related Terms

  • cytoskeleton
  • cell adhesion molecule
  • epithelia
  • zonula occludens
  • blood-brain barrier

Examples of Claudins in the following topics:

  • Tight Junctions

    • The occludins and claudins are the major components of tight junction strands.
  • Intercellular Junctions

    • The cells are held tightly against each other by proteins (predominantly two proteins called claudins and occludins).
  • Blood-Brain Barrier

    • At the interface between blood and the brain, endothelial cells are joined by these tight junctions, which are composed of smaller subunits, frequently biochemical dimers that are transmembrane proteins such as occludin, claudins, and junctional adhesion molecule.
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