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Chapter 12

Mendel's Experiments and Heredity

Book Version 32
By Boundless
Boundless Biology
Biology
by Boundless
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Section 1
Mendel’s Experiments and the Laws of Probability
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Introduction to Mendelian Inheritance

While working with pea plants, Gregor Mendel noticed that offspring were similar to their parent plants, which led him to some of the earliest theories about genetics.

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Mendel’s Model System

The garden pea has several advantageous characteristics that allowed Mendel to develop the laws of modern genetics.

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Mendelian Crosses

Mendel's crosses involved mating two true-breeding organisms that had different traits to produce new generations of pea plants.

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Garden Pea Characteristics Revealed the Basics of Heredity

Mendel's experiments with peas revealed the presence of dominant and recessive traits in the filial generations.

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Rules of Probability for Mendelian Inheritance

The rules of probability can be applied to Mendelian crosses to determine the expected phenotypes and genotypes of offspring.

Section 2
Patterns of Inheritance
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Genes as the Unit of Heredity

Genes exist in pairs within an organism, with one of each pair inherited from each parent.

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Phenotypes and Genotypes

The observable traits expressed by an organism are referred to as its phenotype and its underlying genetic makeup is called its genotype.

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The Punnett Square Approach for a Monohybrid Cross

A Punnett square applies the rules of probability to predict the possible outcomes of a monohybrid cross and their expected frequencies.

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Alternatives to Dominance and Recessiveness

With the inclusion of incomplete dominance, codominance, multiple alleles, and mutant alleles, the inheritance of traits is complex process.

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Sex-Linked Traits

A gene present on one of the sex chromosomes (X or Y in mammals) is a sex-linked trait because its expression depends on the sex of the individual. 

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Lethal Inheritance Patterns

Inheriting two copies of mutated genes that are nonfunctional can have lethal consequences.

Section 3
Laws of Inheritance
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Mendel's Laws of Heredity

Mendel formed the Laws of Heredity (the Law of Segregation and the Law of Independent Assortment) from his pea plant experiments.

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Mendel's Law of Dominance

In a heterozygote, the allele which masks the other is referred to as dominant, while the allele that is masked is referred to as recessive.

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Mendel's Law of Segregation

Mendel's Law of Segregation states that a diploid organism passes a randomly selected allele for a trait to its offspring, such that the offspring receives one allele from each parent.

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Mendel's Law of Independent Assortment

Independent assortment allows the calculation of genotypic and phenotypic ratios based on the probability of individual gene combinations.

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Genetic Linkage and Violation of the Law of Independent Assortment

Genes that are on the same chromosome, or "linked", do not assort independently, but can be separated by recombination.

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Epistasis

Epistasis occurs when one gene masks or interferes with the expression of another.

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Mendel's Experiments and Heredity
  • Mendel’s Experiments and the Laws of Probability
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Modern Understandings of Inheritance
  • Chromosomal Theory and Genetic Linkage
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