Whole genome shotgun sequencing.
In shotgun sequencing, multiple copies of the same chromosome are isolated and then fragmented in random locations. The different copies of the chromosome end up generating different length fragments. When the complete collection of fragments has been sequenced, comparing the sequences of all the fragments will reveal which fragments have ends that overlap with other fragments. The complete sequence from one end of the original DNA to the other can be assembled by following the sequence from the first overlapping fragment to the last.
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