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DNA Structure and Function
DNA Replication
Biology Textbooks Boundless Biology DNA Structure and Function DNA Replication
Biology Textbooks Boundless Biology DNA Structure and Function
Biology Textbooks Boundless Biology
Biology Textbooks
Biology
Concept Version 19
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DNA Replication in Eukaryotes

Replication Fork Formation

Replication Fork Formation

A replication fork is formed by the opening of the origin of replication; helicase separates the DNA strands. An RNA primer is synthesized by primase and is elongated by the DNA polymerase. On the leading strand, only a single RNA primer is needed, and DNA is synthesized continuously, whereas on the lagging strand, DNA is synthesized in short stretches, each of which must start with its own RNA primer. The DNA fragments are joined by DNA ligase (not shown).

Source

    Boundless vets and curates high-quality, openly licensed content from around the Internet. This particular resource used the following sources:

    "OpenStax College, DNA Replication. October 29, 2013."
    http://cnx.org/content/m45475/latest/ OpenStax CNX CC BY 3.0.

Related Terms

  • leading strand
  • origin of replication
  • lagging strand
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