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Cellular Respiration
Oxidation of Pyruvate and the Citric Acid Cycle
Biology Textbooks Boundless Biology Cellular Respiration Oxidation of Pyruvate and the Citric Acid Cycle
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Citric Acid Cycle

The citric acid cycle

The citric acid cycle

In the citric acid cycle, the acetyl group from acetyl CoA is attached to a four-carbon oxaloacetate molecule to form a six-carbon citrate molecule. Through a series of steps, citrate is oxidized, releasing two carbon dioxide molecules for each acetyl group fed into the cycle. In the process, three NAD+ molecules are reduced to NADH, one FAD molecule is reduced to FADH2, and one ATP or GTP (depending on the cell type) is produced (by substrate-level phosphorylation). Because the final product of the citric acid cycle is also the first reactant, the cycle runs continuously in the presence of sufficient reactants.

Source

    Boundless vets and curates high-quality, openly licensed content from around the Internet. This particular resource used the following sources:

    "OpenStax College, Oxidation of Pyruvate and the Citric Acid Cycle. October 16, 2013."
    http://cnx.org/content/m44433/latest/Figure_07_03_02.jpg OpenStax CNX CC BY 3.0.

Related Terms

  • mitochondria
  • Krebs cycle
  • citric acid cycle
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