"Is it safe" is so broad that an answer cannot be given. If you mean "is it absolutely impossible that anyone abuses it, the answer is "no".
However, if you take all the normal precautions (see @Overmind), the printer is quite safe.
It also depends on how secure your network is. If you allow anyone on your network (f.e. by advertising your SSID/code in your shop), you will find that the printer is very exposed, and the set-up is probably not safe. If you are in a rural area, with no-one else in your wifi range, then the set-up should be quite safe. You can also segment your network a bit (even with SOHO routers), making it more secure.
The next question is what your damage would be. Although it is possible to use a printer to gain access to your internal network and try to get data from there, that is rarely done, because other access methods are usually easier. Oh, they might also exhaust your ink and paper stock with, possibly with inappropriate content. Or read-out some of your content from a buffer.
If you don't use WiFi, that limits the attack surface. However, be sure that WiFi is disabled and not 'just not configured' (meaning having all the default values).
Bluetooth is actually less secure than WiFi. The advantage of bluetooth may be that it is a separate network and that its range is shorter than WiFi (most of the time), requiring closer presence.
So yes, if you are in a normal home environment, and you take normal precautions (WPA2, no default passwords, firmware up-to date etc), it should be safe enough.