|  
  
  
 
|  |  |  |  
|  | 
|  |  |  |  
|  | CDC would like to thank the following people for their contributions to the development of the health care provider site: Janet Pregler, M.D., Associate Professor of Clinical Medicine, David Geffen School of Medicine at UCLA, Director, Iris Cantor-UCLA Women's Health Center, Center Director, UCLA National Center of Excellence in Women's Health, and Anne Holohan, Ph. D., Iris Cantor-UCLA Women's Education and Resource Center. |  |  
|  |  |  |  |  |  |  | 
|  |  
|  |  
| It is estimated that between 5 and 10 million people were exposed to diethylstilbestrol (DES) in the US during 1938-1971. DES was thought to be a safe and effective way to prevent miscarriages or premature deliveries. However, later studies revealed that DES had harmful side effects. Many people are still unaware of their exposure to DES and the potential health effects. |  
|  |  
|  | 
| Health Care Providers |  
| This section of CDC's DES Update has 
                                been specifically designed to help health care 
                                providers learn more about DES exposure and its 
                                known health effects to facilitate identifying, 
                                managing, and counseling DES-exposed patients.         |  |  
|  |  
|  |  
|  |  
| 
|  |  
|  |  
| Pharmacology 
  An overview of the pharmacology of DES, data indicating lack of efficacy for DES use as prevention of miscarriage, and clinical indications and current uses for DES. |  
|  |  
| DES Brand Names 
  A list of the most commonly used names and spellings for DES and similar drugs. |  
|  |  
| Resources and Educational Tools 
  A series of educational tools and resources for clinicians and nurses, DES lecture presentation, case studies, self-study module, a listing of DES support organizations, and a DES research bibliography. |  
|  |  |  |  |  | 
|  |  
|  |  
| Information To Identify and Manage DES Patients 
  Research has revealed health effects for women prescribed DES during
								pregnancy and the offspring (DES Sons and Daughters) born of those
								pregnancies. In addition, research is underway to determine if the
								offspring of DES Sons and Daughters might have health effects related to
								DES exposure.  These grandchildren of women prescribed DES during pregnancy
								are sometimes called the "Third Generation." |  
|  |  
| Supplemental DES Materials for Nurses 
  Nurses have an important role in identifying persons 
								who might have been exposed to DES during intake interviews, as well as in counseling patients and assisting in appropriate referrals for further information and treatment. Information in this 
								section will help you facilitate this role. |  
|  |  
|  |  |  |  
|  |  |  |  |  |