hyperpolarize

(verb)

to increase the polarity of something, especially the polarity across a biological membrane

Related Terms

  • saltatory conduction
  • node of Ranvier
  • depolarization
  • action potential

Examples of hyperpolarize in the following topics:

  • Transduction of Light

    • Thus, unlike most other sensory neurons (which become depolarized by exposure to a stimulus), visual receptors become hyperpolarized and are driven away from the threshold .
    • Exposure of the retina to light hyperpolarizes the rods and cones, removing the inhibition of their bipolar cells.
    • As a result, the membrane becomes hyperpolarized.
    • The hyperpolarized membrane does not release glutamate to the bipolar cell.
  • Nerve Impulse Transmission within a Neuron: Action Potential

    • The diffusion of K+ out of the cell hyperpolarizes the cell, making the membrane potential more negative than the cell's normal resting potential.
    • Eventually, the extra K+ ions diffuse out of the cell through the potassium leakage channels, bringing the cell from its hyperpolarized state back to its resting membrane potential.
    • At the same time, Na+ channels close. (4) The membrane becomes hyperpolarized as K+ ions continue to leave the cell.
    • The hyperpolarized membrane is in a refractory period and cannot fire. (5) The K+ channels close and the Na+/K+ transporter restores the resting potential.
  • Synaptic Transmission

    • The neurotransmitter diffuses across the synaptic cleft and binds to ligand-gated ion channels in the postsynaptic membrane, resulting in a localized depolarization or hyperpolarization of the postsynaptic neuron.
  • Balance and Determining Equilibrium

    • The moving otolith layer, in turn, bends the sterocilia to cause some hair cells to depolarize as others hyperpolarize.
  • Nerve Impulse Transmission within a Neuron: Resting Potential

    • At the peak action potential, K+ channels open and the cell becomes (c) hyperpolarized.
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