dephosphorylation

Examples of dephosphorylation in the following topics:

• Termination of the Signal Cascade

  • For example, phosphatases are enzymes that remove the phosphate group attached to proteins by kinases in a process called dephosphorylation.

• Methods of Intracellular Signaling

  • Phosphorylation may activate or inactivate enzymes; the reversal of phosphorylation, dephosphorylation by a phosphatase, will reverse the effect.

• ATP in Metabolism

  • The release of one or two phosphate groups from ATP, a process called dephosphorylation, releases energy.

• Control of Catabolic Pathways

  • Dephosphorylation by a phosphatase reactivates it.

• Regulator Molecules of the Cell Cycle

  • In the active, dephosphorylated state, Rb binds to proteins called transcription factors, most commonly to E2F .