Physiology
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Boundless Anatomy and Physiology
Overview of the Nervous System
Collections of Nervous Tissue
Physiology Textbooks Boundless Anatomy and Physiology Overview of the Nervous System Collections of Nervous Tissue
Physiology Textbooks Boundless Anatomy and Physiology Overview of the Nervous System
Physiology Textbooks Boundless Anatomy and Physiology
Physiology Textbooks
Physiology
Concept Version 10
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Grey and White Matter

The basic pattern of the CNS is a central cavity surrounded by gray matter made up of neuronal cell bodies external to which is the white matter which is made up of myelinated axons. 

Learning Objective

  • Distinguish between grey and white matter of the central nervous system


Key Points

    • The basic pattern of the CNS is a central cavity surrounded by gray matter external to which is the white matter.
    • Gray matter is a major component of the central nervous system, consisting of neuronal cell bodies
    • The white matter is composed of bundles of myelinated axons (not cell bodies) that connect various grey matter regions oelinated axon tracts, and not the cell bodies.
    • Myelin is a thin layer, around the axons of white matter neurons and helps in increasing the speed of electrical transmission. 

Full Text

Grey Matter

The basic pattern of the CNS is a central cavity surrounded by gray matter external to which is the white matter. The spinal cord exhibits this basic pattern, but the brain has additional regions of gray matter not present in the spinal cord. Both the cerebrum and cerebellum have an outer additional layer of gray matter. 

Gray matter is a major component of the central nervous system, consisting of neuronal cell bodies.  Grey matter is distributed at the surface of the cerebral hemispheres and cerebellum, as well as in the depths of the cerebrum, cerebellar, brainstem, and spinal grey matter. 

Grey and White Matter

Micrograph showing grey matter, with the characteristic neuronal cell bodies (right of image - darker pink), and white matter with its characteristic fine mesh work-like appearance (left of image - lighter pink).

White Matter

A second major component of the central nervous system is white matter and it is composed of bundles of myelinated axons that connect various grey matter regions of the nervous system to each other and carry nerve impulses between neurons . White matter only contains the myelinated axon tracts,  and not the cell bodies.  Myelin is a lipid that forms a thin layer, known as the myelin sheath, around the axons.  It acts as an electrical insulator and increases speed of transmission by allowing the signal to jump down the axon. Myelin also gives white matter its characteristic color. 

White Matter on an MRI

This MRI highlights the location of white matter in the brain.

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