Physiology
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Boundless Anatomy and Physiology
Organization at the Tissue Level
Connective Tissue
Physiology Textbooks Boundless Anatomy and Physiology Organization at the Tissue Level Connective Tissue
Physiology Textbooks Boundless Anatomy and Physiology Organization at the Tissue Level
Physiology Textbooks Boundless Anatomy and Physiology
Physiology Textbooks
Physiology
Concept Version 14
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Characteristics of Connective Tissue

Connective tissue is incredibly diverse and contributes to energy storage, the protection of organs, and the body's structural integrity.

Learning Objective

  • Describe the main characteristics and functions of connective tissue


Key Points

    • Connective tissue is the most abundant and widely distributed of the primary tissues. 
    • Connective tissue has three main components: cells, fibers, and ground substance. Together the ground substance and fibers make up the extracellular matrix. 
    • Connective tissue is classified into two subtypes: soft and specialized connective tissue. 
    • Major functions of connective tissue include: 1) binding and supporting, 2) protecting, 3) insulating, 4) storing reserve fuel, and 5) transporting substances within the body.
    • Connective tissues can have various levels of vascularity. Cartilage is avascular, while dense connective tissue is poorly vascularized. Others, such as bone, are richly supplied with blood vessels.

Terms

  • fibroblast

    A type of cell found in connective tissue that synthesizes the extracellular matrix and collagen. 

  • connective tissue

    A type of tissue found in animals whose main function is to bind, support, and anchor the body.

  • extracellular matrix

    Cells of the connective tissue are suspended in a non-cellular matrix that provides structural and biochemical support to the surrounding cells.


Full Text

Connective tissue (CT) is a one of the four main classes of tissues. Although it is the most abundant and widely distributed of the primary tissues, the amount of connective tissue in a particular organ varies. Like to the timber framing of a house, the connective tissue provides structure and support throughout the body.

Structure of Connective Tissue

Connective tissue has three main components: 

  1. Ground substance. 
  2. Fibers.
  3. Cells. 

Together the ground substance and fibers make up the extracellular matrix. The composition of these three elements vary tremendously from one organ to the other. This offers great diversity in the types of connective tissue. 

Ground substance is a clear, colorless, viscous fluid that fills the space between the cells and fibers. It is composed of proteoglycans and cell adhesion proteins that allow the connective tissue to act as glue for the cells to attach to the matrix. The ground substance functions as a molecular sieve for substances to travel between blood capillaries and cells. 

Connective tissue fibers provide support. Three types of fibers are found in connective tissue:

  1. Collagen.
  2. Elastic fibers.
  3. Reticular fibers.   

Collagen Fibers

Collagen fibers are fibrous proteins and are secreted into the extracellular space and they provide high tensile strength to the matrix. 

Elastic Fibers

Elastic fibers are long, thin fibers that form branching network in the extracellular matrix. They help the connective tissue to stretch and recoil. 

Reticular Fibers

Reticular fibers are short, fine collagenous fibers that can branch extensively to form a delicate network. 

Collagen

Collagen fibers are the strongest and most abundant of all the connective tissue fibers. 

This is a black and white x-ray of collagen fibers, the strongest and most abundant of all the connective tissue fibers.

Structural elements of connective tissue

Connective tissues consist of three parts: cells suspended in a ground substance or matrix; and most have fibers running through it.

This is a drawing of the structural elements of connective tissue. It depicts cells suspended in a ground substance or matrix, with elastic and collagen fibers running throughout the matrix. CT is classified into two subtypes: soft CT and specialized CT. The soft CT subtype—loose, dense, and elastic tissues—are found in parts of our skin, tendons and blood vessels. The special CT subtype includes cartilage, bone, adipose tissue, blood, and lymphatic tissue, and provides a structural framework for the body and connects body tissues.

Function of Connective Tissue

The major functions of connective tissue include:

  1. Binding and supporting. 
  2. Protecting. 
  3. Insulating. 
  4. Storing reserve fuel. 
  5. Transporting substances within the body.
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