warfarin

(noun)

An anticoagulant medication that is used for the prophylaxis of thrombosis and embolism in many disorders.

Related Terms

  • tenase
  • oxidized
  • coumarin

Examples of warfarin in the following topics:

  • Anticoagulants

    • However, if you are taking warfarin to prevent heart attacks, then it is necessary to control intake of leafy green vegetables since warfarin is an antagonist to vitamin K and could work improperly if the diet is high in vitamin K.
    • Coumadins such as warfarin are oral anticoagulant pharmaceuticals that antagonize the effects of vitamin K1.
  • Role of Vitamin K

    • Vitamin K can be inhibited by the anticoagulant drug warfarin, which acts as an antagonist for vitamin K.
    • Warfarin is used in medicine for those at high risk of thromboembolism to prevent the coagulation cascade by reducing vitamin K dependent synthesis of coagulation factors.
    • Warfarin's effects can be overcome by ingesting more vitamin K to reactivate the coagulation factor synthesis pathway.
  • Teratogens

    • Women with indications for warfarin therapy should either abstain from pregnancy or switch to low molecular weight heparins.
    • Warfarin typically produces mental retardation, growth restriction, nasal hypoplasia, and opthalmic abnormalities.
  • Fibrinolysis

    • Warfarin inhibits vitamin K cofactor activation during the coagulation cascade, and citrates chelate calcium to prevent prothrombin activation into thrombin.
  • Transient Ischemic Attacks

    • Example drugs used to prevent future TIAs include anti-coagulant medications, like heparin and warfarin, and anti-platelet medications such as aspirin.
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