second-class lever

(noun)

Load between force and pivot.

Related Terms

  • Levers can also vary based on the relative position of the load, pivot, and point of force application.
  • Flexion
  • extensors
  • Abduction
  • adduction
  • third-class lever
  • first class lever
  • abduction
  • rotation
  • origin
  • insertion
  • flexion
  • extension
  • flexor
  • extensor

Examples of second-class lever in the following topics:

  • Lever Systems

    • Classes of levers include:
    • In a second-class lever, the force is applied at one end with the pivot at the other and the load in between.
    • Second-class levers are also relatively uncommon in the body.
    • All second-class levers in the body act at a mechanical advantage since the force is always applied closer to the load than to the pivot.
    • In a third-class lever the force is applied between the load and the pivot.
  • Direct Gene Activation and the Second-Messenger System

    • Nuclear receptors can be classified into two broad classes according to their mechanism of action and sub-cellular distribution in the absence of ligand.
    • For lipophobic hormones which cannot pass the cellular membrane activity is mediated and amplified within a cell by the action of second messenger mechanisms (molecules which relay signals from receptors on the cell surface to target molecules inside the cell in the cytoplasm or nucleus).
    • General schematic of second messenger generation following activation of membrane bound receptors.
    • This figure depicts the mechanism of a class I nuclear receptor (NR) that, in the absence of ligand, is located in the cytosol.
    • Distinguish between the hormone mechanisms of direct gene activation and second-messenger system
  • Mechanisms of Hormone Action

    • Water-soluble hormones such as Epinephrine, bind to a cell-surface localized receptor, initiating a signaling cascade using intracellular second messengers.
  • Pain Sensation

    • The Aδ fiber axons are myelinated and can allow an action potential to travel at a rate of about 20 meters/second towards the central nervous system.
    • These only conduct at speeds of around 2 meters/second.
    • The first phase is mediated by the fast-conducting Aδ fibers, and the second part is due to C fibers.
    • The second phase is a more prolonged and slightly less intense feeling of pain as a result of the damage.
    • Aδ fibers are thinly myelinated; therefore, they conduct signals more rapidly than unmyelinated C fibers, but more slowly than other, more thickly myelinated "A" class fibers.
  • Complete Antigens and Haptens

    • After a second exposure later, the proliferated T cells can become activated, generating an immune reaction, producing the typical blisters of poison ivy exposure.
    • This also appears to be the mechanism by which the anesthetic gas halothane can cause a life-threatening hepatitis, as well as the mechanism by which penicillin-class drugs cause autoimmune hemolytic anemia.
  • Overview of Adaptive Immunity

    • The antigen is processed by the APC and bound to MHC class II receptors and MHC class I receptors on the cell membrane of the APC.
    • In this manner, the second and subsequent exposures to an antigen produce a stronger and faster immune response.
  • Adrenergic Neurons and Receptors

    • The adrenergic receptors (or adrenoceptors) are a class of metabotropic G protein-coupled receptors that are targets of the catecholamines, especially norepinephrine or noradrenaline, as seen in , and epinephrine (adrenaline) as shown in ).
    • Agonist binding thus causes a rise in the intracellular concentration of the second messenger cAMP.
  • Congenital Adrenal Hyperplasia

    • Production begins in the second month of fetal life.
    • The resulting excessive or deficient production of these three classes of hormones produce the most important problems for people with CAH.
  • Types of Epithelial Tissue

    • The first name describes the number of cell layers present and the second describes the shape of the cells.
    • The four major classes of simple epithelium are: 1) simple squamous; 2) simple cuboidal; 3) simple columnar; and 4) pseudostratified.
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