cytolytic

(adjective)

Of or pertaining to cytolysis

Related Terms

Examples of cytolytic in the following topics:

  • Classes of T Cells

    • Effector cells include helper T cells, and cytolytic or cytotoxic T cells.
    • Cytolytic or cytotoxic T cells (characterized by the expression of CD8 marker on their surface) kill cells that produce foreign antigens, such as cells infected by viruses and other intracellular microbes .

  • T Cell Receptors

    • The antigen receptor of MHC-restricted CD4 helper T cells and CD8 cytolytic T cell is a heterodimer consisting of two transmembrane polypeptide chains, designated alpha and beta, covalently linked to each other by disulfide bonds.

  • Natural Killer Cells

    • NK cells paralyze target cells using the cytolytic protein perforin and a variety of protease enzymes.
    • Functions of NK cells include: Cytolytic Granule Mediated Cell Apoptosis; Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC); Cytokine induced NK and CTL activation; Missing 'self' hypothesis; Tumor cell surveillance; NK cell function in adaptive response; NK cell function in pregnancy; and NK cell evasion by tumor cells .

  • Interferons

    • As an infected cell dies from a cytolytic virus, viral particles are released that can infect nearby cells.

  • The Complement System

    • MAC is the cytolytic endproduct of the complement cascade; it forms a transmembrane channel, which causes osmotic lysis of the target cell.