ATP citrate lyase

(noun)

ATP citrate lyase is an enzyme that represents an important step in fatty acid biosynthesis. This step in fatty acid biosynthesis occurs because ATP citrate lyase is the link between the metabolism of carbohydrates (which causes energy) and the production of fatty acids.

Related Terms

  • carboxylation
  • Krebs cycle

Examples of ATP citrate lyase in the following topics:

  • The Reverse TCA Cycle

    • The enzymes, unique to reverse TCA, that function in catalyzing these reactions include: ATP citrate lyase, 2-oxoglutarate:ferredoxin oxidoreductase, and pyruvate:ferredoxin oxidoreductase.
    • ATP citrate lyase is one of the key enzymes that function in reverse TCA.
    • ATP citrate lyase is the enzyme responsible for cleaving citrate into oxaloacetate and acetyl CoA.
    • 8) ATP citrate lyase is then used to convert citrate to oxaloacetate and acetyl CoA (ATP is hydrolyzed to ADP and Pi).
    • List the enzymes and function that are unique to the reverse TCA cycle (ATP citrate lyase; 2-oxoglutarate:ferredoxin oxidoreductase; pyruvate:ferredoxin oxidoreductase)
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