Vasculitis

(noun)

Inflammation of the vessel wall due to an infection or autoimmune disease.

Related Terms

  • myocarditis
  • bacteremia
  • Endocarditis
  • lymphadenopathy

Examples of Vasculitis in the following topics:

  • Immune Complex Autoimmune Reactions

    • Immune complexes may cause disease when they are deposited in organs, e.g. in certain forms of vasculitis.
    • Typical of most mechanisms of the type III hypersensitivity, Arthus manifests as local vasculitis due to deposition of IgG-based immune complexes in dermal blood vessels.
  • Type III (Immune Complex) Reactions

    • Hence, vasculitis, glomerulonephritis and arthritis are commonly-associated conditions as a result of type III hypersensitivity responses.
    • As observed under methods of histopathology, acute necrotizing vasculitis within the affected tissues is observed concomitant to neutrophilic infiltration, along with notable eosinophilic deposition (fibrinoid necrosis).
    • Immune complexes may themselves cause disease when they are deposited in organs, e.g. in certain forms of vasculitis.
  • The Cardiovascular System

    • Vasculitis is inflammation of the vessel wall due to an infection (or autoimmune disease).
    • Compare and contrast the causes associated with: endocarditis, myocarditis, bacteremia, vasculitis and lymphatic disease
  • Dermatomyositis and Polymyositis

    • ., coexist with or are part of a spectrum that includes) other autoimmune diseases such as Sjögren's syndrome, lupus, scleroderma, or vasculitis.
    • It presents as a proximal symmetrical muscle weakness with vasculitis affecting the skin, muscles, and internal organs.
  • Glomerular Diseases

    • Secondary causes are associated with certain infections (bacterial, viral, or parasitic pathogens), drugs, systemic disorders (SLE or vasculitis), or diabetes.
  • Urinalysis

    • Red blood cell casts – associated with glomerulonephritis, vasculitis, or malignant hypertension
  • Systemic Lupus Erythematosus

    • Intravenous immunoglobulins may be used to control SLE with organ involvement, or vasculitis.
  • Artificial Blood Substitutes

    • Synthetic oxygen carriers may also show potential for cancer treatment, as their reduced size allows them to diffuse more effectively through poorly-vasculated tumor tissue, increasing the effectiveness of treatments like photodynamic therapy and chemotherapy.
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