trypsin

(noun)

A digestive enzyme that cleaves peptide bonds (a serine protease).

Related Terms

Examples of trypsin in the following topics:

  • Chemical Digestion of Carbohydrates, Proteins, Lipids, and Nucleic Acids

    • Protein digestion occurs in the stomach and the duodenum through the action of three primary enzymes: pepsin, secreted by the stomach, and trypsin and chymotrypsin, secreted by the pancreas.
    • Thus, trypsin is secreted by the pancreas in the form of trypsinogen, which is activated in the duodenum by enterokinase to form trypsin.
    • Trypsin then cleaves proteins to smaller polypeptides.

  • Associated Organs

    • These zymogens are inactivated forms of trypsin and chymotrypsin.
    • Once released in the intestine, the enzyme enterokinase, which is produced by the intestinal mucosa, activates trypsinogen by cleaving it to form trypsin.
    • The free trypsin then cleaves the rest of the trypsinogen and chymotrypsinogen to their active forms.

  • Tissue Culture of Animal Viruses

    • To prepare cell cultures, tissue fragments are first dissociated, usually with the aid of trypsin or collagenase.

  • Digestive Processes of the Small Intestine

    • Proteolytic enzymes, including trypsin and chymotrypsin, secreted by the pancreas, cleave proteins into smaller peptides.

  • Diphtheria

    • Inside the endosome, the toxin is split by a trypsin-like protease into its individual A and B fragments.

  • Mapping Protein-Protein Interactions

    • Purified protein complexes are then resolved on native gels and discrete protein bands are excised and digested into small peptide fragments by trypsin.

  • Hydrolysis

    • Proteins are broken down by the enzymes trypsin, pepsin, peptidase and others.

  • Digestive Properties of the Stomach

    • The biological effects of salivary EGF include healing of oral and gastroesophageal ulcers, inhibition of gastric acid secretion, and stimulation of DNA synthesis as well as mucosal protection from intraluminal injurious factors such as gastric acid, bile acids, pepsin, and trypsin, and to physical, chemical, and bacterial agents.

  • Types and Functions of Proteins

    • These enzymes include amylase, which catalyzes the digestion carbohydrates in the mouth and small intestine; pepsin, which catalyzes the digestion of proteins in the stomach; lipase, which catalyzes reactions need to emulsify fats in the small intestine; and trypsin, which catalyzes the further digestion of proteins in the small intestine.

  • Enzymes Used in Industry

    • Trypsin is used to predigest baby foods.