thrombopoietin

Examples of thrombopoietin in the following topics:

• Medical Uses of Hematopoietic Growth Factors

  • Thrombopoietin shows great promise for preventing platelet depletion during chemotherapy.
  • CSFs and thrombopoietin also improve the outcome of patients who receive bone marrow transplants.
  • Despite numerous trials, thrombopoietin is not used therapeutically.
  • Trials of a modified recombinant form, megakaryocyte growth and differentiation factor (MGDF), were stopped when healthy volunteers developed autoantibodies to endogenous thrombopoietin and then developed thrombocytopenia themselves.
  • Thrombopoietin is a glycoprotein hormone produced mainly by the liver and the kidney that regulates the production of platelets by the bone marrow.

• Platelet Formation

  • Megakaryocyte and platelet production is regulated by thrombopoietin, a hormone produced by the liver and kidneys.

• Development of Blood

  • On the other hand, thrombopoietin makes myeloid progenitor cells differentiate to megakaryocytes, which produce platelets.

• Components of Blood

  • Their production is regulated by the hormone called Thrombopoietin.