sickle

(noun)

Hand-held agricultural tool with a variously curved blade typically used for harvesting grain crops or cutting succulent forage (either freshly cut or dried as hay) used chiefly to feed livestock.

Related Terms

  • husbandry
  • kinsman
  • agrarian

Examples of sickle in the following topics:

  • Sickle-Cell Disease

    • Sickle-cell disease is an autosomal recessive genetic blood disorder in which red blood cells assume a rigid sickle shape.
    • Sickle-cell disease (SCD), or sickle-cell anemia, is an autosomal recessive genetic blood disorder with overdominance characterized by red blood cells that assume an abnormal, rigid, and sickle shape.
    • Sickle cell can be diagnosed by a blood test.
    • Some exhibit the normal donut-shaped morphology while others exhibit the sickle shape characteristic of those with sickle-cell trait or sickle-cell disease.
    • The inset image shows a cross-section of a sickle cell with abnormal (sickle) hemoglobin forming abnormal strands.
  • Race and Ethnicity

    • Also, sickle-cell anemia is most prevalent in populations of sub-Saharan African ancestry, but it is also common among Latin-American, Indian, Saudi Arab, and Mediterranean populations, such as Turkey, Greece, and Italy.
    • Some diseases may also be influenced by genes that differ in frequency between groups, such as sickle-cell anemia, which occurs overwhelmingly among some black populations, although the significance in clinical medicine of race categories as a proxy for exact genotypes of individuals has been questioned.
    • Taking the example of sickle-cell disease, in an emergency room, knowing the geographic origin of a patient may help a doctor doing an initial diagnosis if a patient presents with symptoms compatible with this disease.
    • In the United States, screening for sickle cell anemia is done on all newborns regardless of race.
  • Transport of Oxygen in the Blood

    • Diseases such as sickle cell anemia and thalassemia decrease the blood's ability to deliver oxygen to tissues and its oxygen-carrying capacity.
    • In sickle cell anemia, the shape of the red blood cell is crescent-shaped, elongated, and stiffened, reducing its ability to deliver oxygen .
    • Individuals with sickle cell anemia have crescent-shaped red blood cells.
  • Protein Structure

    • In sickle cell anemia, a single amino substitution in the hemoglobin β chain causes a change the structure of the entire protein.
    • These dysfunctional hemoglobin proteins, under low-oxygen conditions, start associating with one another, forming long fibers made from millions of aggregated hemoglobins that distort the red blood cells into crescent or "sickle" shapes, which clog arteries .
  • Artifacts of Assyria

    • The kings stands stiffly with a sickle in his right hand (at his side) and a mace in his left, which he holds to his torso.
    • Both objects are symbolic; the sickle was used as a weapon against monsters, while the mace was a symbol of political and religious authority.
    • He holds a sickle as a form of mythological defense and a mace as a symbol of authority.
  • Exceptions to Koch's Postulates

    • Noninfection may be due to such factors as general health and proper immune functioning; acquired immunity from previous exposure or vaccination; or genetic immunity, as with the resistance to malaria conferred by possessing at least one sickle cell allele.
  • RBC Anatomy

    • This occurs in people with spherocytic (sphere-shaped) anemia or sickle-cell anemia.
  • Autoimmune Diseases

    • In contrast to classical inherited genetic diseases, like sickle cell anemia, autoimmune diseases are not caused by the defect of a single gene, but by the dysfunction of the complex interaction of a group of genes.
  • Binomial distribution exercises

    • Sickle cell anemia is a genetic blood disorder where red blood cells lose their flexibility and assume an abnormal, rigid, "sickle" shape, which results in a risk of various complications.
  • References

    • . & VanSickle, R.
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