retrogene

(noun)

a DNA gene copied back from RNA by reverse transcription

Related Terms

  • paralogous
  • genetic drift
  • nondisjunction

Examples of retrogene in the following topics:

  • Gene Duplications and Divergence

    • If viral proteins attach irregularly to cellular mRNA, they can reverse-transcribe copies of genes to create retrogenes.
    • Retrogenes usually lack intronic sequence and often contain poly A sequences that are also integrated into the genome.
    • Many retrogenes display changes in gene regulation in comparison to their parental gene sequences, which sometimes results in novel functions.
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