hypoplasia

(noun)

Underdevelopment or incomplete development of a tissue or organ, especially when caused by an inadequate or below-normal number of cells.

Related Terms

  • cyanosis
  • long QT syndrome

Examples of hypoplasia in the following topics:

  • Congenital Heart Defects

    • Hypoplasia can affect the heart, typically resulting in the underdevelopment of the right ventricle or the left ventricle.
    • Hypoplasia of the heart is rare, but is the most serious form of CHD.
    • Hypoplasia of the heart is generally a cyanotic heart defect.
  • Teratogens

    • Warfarin typically produces mental retardation, growth restriction, nasal hypoplasia, and opthalmic abnormalities.
    • Angiotensin converting enzyme (ACE) inhibitors will cause fetal renal failure and oligohydramnios that lead to pulmonary hypoplasia and limb contracture.
  • Polycystic Kidney Disease

    • Unfortunately, resulting hypoplasia results in a 30% death rate in neonates with ARPKD.
  • Plant Viruses

    • Other viruses induce hypoplasia, or decreased cell growth, in the leaves of plants, causing thin, yellow areas to appear.
  • Pregnancy-Induced Hypertension

    • The fetus is at increased risk for a variety of life-threatening conditions, including pulmonary hypoplasia (immature lungs).
  • Primary Immunodeficiency Diseases

    • Various immuno-osseous dysplasias (abnormal development of the skeleton with immune problems);for example, cartilage-hair hypoplasia, Schimke syndrome
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