glucan

Examples of glucan in the following topics:

• Antifungal Drugs

  • Cell wall synthesis requires the production of glucan by the enzyme 1,3-β glucan synthase.
  • Echinocandins specifically inhibit glucan synthesis by targeting that enzyme.
  • Caspofungin blocks cell-wall synthesis by disrupting glucan synthesis; it can target invasive candidiasis and aspergillus.

• Fungi Cell Structure and Function

  • The rigid layers of fungal cell walls contain complex polysaccharides called chitin and glucans.