epiphyseal plate

Examples of epiphyseal plate in the following topics:

• Growth of Bone

  • The epiphyseal plate is the area of growth in a long bone.
  • On the epiphyseal side of the epiphyseal plate, cartilage is formed.
  • All that remains of the epiphyseal plate is the epiphyseal line .
  • As a bone matures, the epiphyseal plate progresses to an epiphyseal line.
  • (b) Epiphyseal lines are the remnants of epiphyseal plates in a mature bone.

• Cartilaginous Joints: Synchodroses

  • A temporary form of joint called an epiphyseal (growth) plate, is one where the cartilage is converted into bone before adult life.
  • The epiphyseal plate is a hyaline cartilage plate in the metaphysis at each end of a long bone.
  • The epiphyseal plate is found in children and adolescents.
  • In puberty, increasing levels of estrogen, in both females and males, leads to increased apoptosis of chondrocytes in the epiphyseal plate.
  • In adults who have stopped growing, the plate is replaced by an epiphyseal line.

• Development of Joints

  • Between the epiphysis and diaphysis (the long midsection of the long bone) lies the metaphysis, including the epiphyseal plate (growth plate) .
  • At the joint, the epiphysis is covered with articular cartilage; below that covering is a zone similar to the epiphyseal plate, known as subchondral bone.
  • For example, the head of the femur (which is a part of the hip joint complex) is a pressure epiphyses.
  • These epiphyses assist in transmitting the weight of the human body and are the regions of the bone which is under pressure during movement or locomotion; hence, their name.
  • Image shows the location of the epiphyseal plates (or lines) and the articular surfaces of long bones.

• Postnatal Bone Growth

  • Secondary ossification occurs after birth at the epiphyses of long bones and continues until skeletal maturity.
  • It forms the epiphyses of long bones and the extremities of irregular and flat bones.
  • The diaphysis and both epiphyses of a long bone are separated by a growing zone of cartilage (the epiphyseal plate).
  • When a child reaches skeletal maturity (18 to 25 years of age), all of the cartilage is replaced by bone, fusing the diaphysis and both epiphyses together (epiphyseal closure).
  • Between the epiphysis and diaphysis (the long midsection of the long bone) lies the metaphysis, including the epiphyseal plate (growth plate).

• Supply of Blood and Nerves to Bone

  • Near the epiphysis, they anastomose with the metaphyseal and epiphyseal arteries.
  • The blood supply of the immature bones is similar, but the epiphysis is a discrete vascular zone separated from the metaphysis by the growth plate.
  • Epiphyseal and metaphyseal arteries enter on both sides of the growth cartilage, with anastamoses between them being few or absent.
  • Image shows the location of the epiphyseal plates (or lines) and the articular surfaces of long bones.

• Structural Classification of Joints

  • The epiphyseal (growth) plates are examples of synchondroses.
  • Image demonstrates a synchondrosis joint with epiphyseal plate (temporary hyaline cartilage joint) indicated (a) and a symphysis joint (b).

• Stages of Bone Development

  • Secondary ossification occurs after birth, and forms the epiphyses of long bones and the extremities of irregular and flat bones.
  • The diaphysis and both epiphyses of a long bone are separated by a growing zone of cartilage (the epiphyseal plate).
  • When the child reaches skeletal maturity (18 to 25 years of age), all of the cartilage is replaced by bone, fusing the diaphysis and both epiphyses together (epiphyseal closure).

• Bone Development

  • The bone continues to grow and elongate as the cartilage cells at the epiphyses divide.
  • In the last stage of prenatal bone development, the centers of the epiphyses begin to calcify.
  • Secondary ossification centers form in the epiphyses as blood vessels and osteoblasts enter these areas and convert hyaline cartilage into spongy bone.
  • Until adolescence, hyaline cartilage persists at the epiphyseal plate (growth plate), which is the region between the diaphysis and epiphysis that is responsible for the lengthwise growth of long bones.

• Gross Anatomy

  • The ends of epiphyses are covered with hyaline cartilage (articular cartilage).
  • At the cessation of growth, the epiphyses fuse to the diaphysis, thus obliterating the intermediate area known as the epiphyseal plate or growth plate.
  • These bones are expanded into broad, flat plates, as in the cranium (skull), ilium (pelvis), sternum, rib cage, sacrum, and scapula.

• Hormonal Abnormalities and Height

  • Acromegaly is a syndrome that results when the anterior pituitary gland produces excess growth hormone (GH) after epiphyseal plate closure at puberty.
  • The distinction between gigantism (occurring in children) and acromegaly (occurring in adults) can be made by the occurrence of the adenoma in relation to the closure of the epiphyses.
  • If elevated growth hormone levels occur before the closure of the epiphyses (i.e. in prepubertal children), then gigantism ensues.
  • If it occurs after the closure of the epiphyses (i.e., in adults), then acromegaly ensues.