dystrophin

(noun)

A cytoplasmic structural protein that is deficient in some forms of muscular dystrophy.

Related Terms

Examples of dystrophin in the following topics:

  • Muscular Dystrophy

    • Specifically the proteins dystrophin and the dystrophin protein complexes are altered and nonfunctional, unable to join with actin filaments.
    • However, mutations of the dystrophin gene and nutritional defects (with no genetics history) at the prenatal stage are also possible in about 33% of people affected by DMD.
    • In affected muscle the tissue becomes disorganized and the concentration of dystrophin (green) is greatly reduced.

  • Muscular Atrophy

    • The most common types of muscular dystrophy appear to be due to a genetic deficiency of the muscle protein dystrophin.