dominant lethal

(adjective)

an inheritance pattern is one in which an allele is lethal both in the homozygote and the heterozygote; this allele can only be transmitted if the lethality phenotype occurs after reproductive age

Related Terms

  • mutation
  • recessive lethal

Examples of dominant lethal in the following topics:

  • Lethal Inheritance Patterns

    • In other instances, the recessive lethal allele might also exhibit a dominant (but not lethal) phenotype in the heterozygote.
    • The dominant lethal inheritance pattern is one in which an allele is lethal both in the homozygote and the heterozygote; this allele can only be transmitted if the lethality phenotype occurs after reproductive age.
    • Individuals with mutations that result in dominant lethal alleles fail to survive even in the heterozygote form.
    • Dominant lethal alleles are very rare because, as you might expect, the allele only lasts one generation and is not transmitted.
    • However, just as the recessive lethal allele might not immediately manifest the phenotype of death, dominant lethal alleles also might not be expressed until adulthood.
  • Humans and Electric Hazards

    • Shocks range in severity from painful but otherwise harmless to heart-stoppingly lethal.
    • The lethality of an electric shock is dependent on several variables:
    • Current: The higher the current, the more likely it is lethal.
    • Duration: The longer the duration, the more likely it is lethal -- safety switches may limit the time of current flow.
    • Pathway: If current flows through the heart muscle, it is more likely to be lethal.
  • Genetic Defects from Radiation

    • Initial stage: the first 1–9 weeks; the period with the greatest number of deaths—90 percent due to thermal injury and/or blast effects and 10 percent due to super-lethal radiation exposure.
    • Intermediate stage: from 10–12 weeks; deaths in this period are from ionizing radiation in the median lethal range.
  • Ashoka's Conversion

    • The lethal war with Kalinga transformed the vengeful Emperor Ashoka into a stable and peaceful emperor, and he became a patron of Buddhism.
    • Throughout Theravada Southeastern Asia, the model of rulership embodied by Ashoka replaced the notion of divine kingship that had previously dominated (in the Angkor kingdom, for instance).
  • Biological Effects of Radiation

    • Ionizing radiation is generally harmful, even potentially lethal, to living organisms.
    • Ionizing radiation is generally harmful, even potentially lethal, to living organisms.
  • Privacy Rights and the Right to Die

    • The key difference between euthanasia and PAD is who administers the lethal dose of medication.
    • The patient must be of sound mind when they request a prescription for a lethal dose of medication.
  • Anthrax

    • Most forms of the disease are lethal, and it affects both humans and animals.
    • This is known as inhalation anthrax or pulmonary anthrax and can cause serious, sometimes lethal respiratory disease.
  • Tuberculosis

    • Tuberculosis is a common, and in many cases lethal, infectious bacterial disease that mainly affects the lungs.
    • Tuberculosis (TB; short for tubercle bacillus) is a common, and in many cases lethal, infectious disease caused by various strains of mycobacteria, usually Mycobacterium tuberculosis .
  • Paralysis

    • A well-known example is the tetrodotoxin of fish species such as Takifugu rubripes, the famously lethal pufferfish of Japanese fugu.
    • A non-lethal dose of this toxin results in temporary paralysis.
    • Tetrodotoxin, frequently abbreviated as TTX, is a potent neurotoxin with no known antidote, produced by the lethal pufferfish used for Japanese fugu.
  • Plant Defenses Against Pathogens

    • Many metabolites are toxic and can even be lethal to animals that ingest them.
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