cytogenetic

Examples of cytogenetic in the following topics:

• Physical Maps and Integration with Genetic Maps

  • Physical maps display the physical distance between genes and can be constructed using cytogenetic, radiation hybrid, or sequence mapping.
  • There are three methods used to create a physical map: cytogenetic mapping, radiation hybrid mapping, and sequence mapping.
  • Cytogenetic mapping uses information obtained by microscopic analysis of stained sections of the chromosome .
  • A cytogenetic map shows the appearance of a chromosome after it is stained and examined under a microscope.
  • Describe the methods used to physically map genes: cytogenetic mapping, radiation hybrid mapping, and sequence mapping

• The FISH Technique

  • FISH (fluorescence in situ hybridization) is a cytogenetic technique developed by biomedical researchers in the early 1980s.

• Identification of Chromosomes and Karyotypes

  • The isolation and microscopic observation of chromosomes forms the basis of cytogenetics and is the primary method by which clinicians detect chromosomal abnormalities in humans.

• Chromosomal Structural Rearrangements

  • Humans and chimpanzees differ cytogenetically by pericentric inversions on several chromosomes and by the fusion of two separate chromosomes in chimpanzees that correspond to chromosome two in humans.