bubonic plague

World History

(noun)

Disease circulating mainly in fleas on small rodents. Without treatment, the bacterial infection kills about two thirds of infected humans within four days.

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Microbiology

(noun)

a contagious, often fatal, epidemic disease caused by the bacterium Yersinia pestis, transmitted by the bite of fleas from an infected person or rodent, especially a rat, and characterized by delirium, chills, fever, vomiting, diarrhea, and the formation of buboes

Related Terms

  • plague
  • hepatosplenomegaly
  • pneumonic plague

Examples of bubonic plague in the following topics:

  • History of Bacterial Diseases

    • From 541 to 750 C.E.., an outbreak of what was likely a bubonic plague (the Plague of Justinian), eliminated one-quarter to one-half of the human population in the eastern Mediterranean region.
    • The bubonic plague would strike Europe more than once.
    • Bubonic plague struck London hard again in the mid-1600s .
    • Although contracting bubonic plague before antibiotics meant almost certain death, the bacterium responds to several types of modern antibiotics; mortality rates from plague are now very low.
    • Such was the case with bubonic plague.
  • Plague

    • Human Y. pestis infection is manifested in three main forms: pneumonic, septicemic, and the notorious bubonic plagues.
    • Although bubonic plague is often used synonymously with plague, it refers specifically to an infection that enters through the skin and travels through the lymph nodes (buboes).
    • The incubation period of bubonic plague is from 2-6 days, while the bacteria actively replicate.
    • Pneumonic plague manifests as a severe lung infection, and is more virulent and rare than bubonic plague.
    • Scanning electron micrograph depicting a mass of Yersinia pestis bacteria (the cause of bubonic plague) in the foregut of the flea vector.
  • The Black Death

    • The Black Death was an infamous pandemic of bubonic plague and one of the most devastating pandemics in human history.
    • In the Late Middle Ages (1340–1400) Europe experienced the most deadly disease outbreak in history when the Black Death, the infamous pandemic of bubonic plague, hit in 1347.
    • The most infamous symptom of bubonic plague is an infection of the lymph glands, which become swollen and painful and are known as buboes.
    • Buboes associated with the bubonic plague are commonly found in the armpits, groin, and neck region.
    • Plague brought an eventual end of serfdom in Western Europe.
  • Arthropods as Vectors

    • The human flea, Pulex irritans, and the Oriental rat flea , Xenopsylla cheopis, are responsible for the transmission of the bubonic plague, murine typhus, and tapeworms.
    • The oriental rat flea is an example of an arthropod vector as it is the primary vector of plague.
    • This vector has been the cause of large plague epidemics in Asia, Africa, and South America.
  • Disease Reservoirs and Epidemics

    • Bubonic plague: marmots, black rats, prairie dogs, chipmunks, and squirrels for bubonic plague
    • The migrations of certain animals, such as rats, are in some cases responsible for the spread of plague, from which these animals die in great numbers.
  • Tularemia

    • Tularemia (also known as Pahvant Valley plague, rabbit fever, deer fly fever, and Ohara's fever) is a serious infectious disease caused by the bacterium Francisella tularensis.
    • Inflammation spreads to the lymph nodes, which enlarge and may suppurate (mimicking bubonic plague), accompanied by a high fever.
  • Overcoming Density-Dependent Regulation

    • In the fourteenth century, the bubonic plague killed as many as 100 million people: between 30 to 60 percent of Europe's population.
    • Today, however, the plague and other infectious diseases have much less of an impact.
  • Koch and Pure Culture

    • By using his methods, Koch's pupils found the organisms responsible for diphtheria, typhoid, pneumonia, gonorrhoea, cerebrospinal meningitis, leprosy, bubonic plague, tetanus, and syphilis.
  • Pisa, Venice, and Milan

    • Additionally, the power of the church continued to grow in this period, particularly during the wave of Bubonic Plague that killed as much as a quarter of the population in some cities.
  • Living in Europe

    • Additionally, the Black Death caused by the Bubonic Plague killed nearly half the population of Europe through successive waves.
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